1767-P: “Leader” ß-Cells within the Pancreatic Islet Are a Functionally Stable Subpopulation In Vitro and In Vivo

β-cell coordination within the islet is critical for normal glucose-stimulated insulin secretion. Recently, we and others have identified a subpopulation of β-cells termed “leaders” which are the first cells to show an increase intracellular Ca2+ during glucose-induced Ca2+ waves. In the Zebrafish,...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2023-06, Vol.72 (Supplement_1), p.1
Hauptverfasser:	DELGADILLO SILVA, LUIS F., RUTTER, GUY A., CHABOSSEAU, PAULINE L., PROVENCHER-GIRARD, AUDREY, PRAT, ALEXANDRE, LOPEZ NORIEGA, LIVIA
Format:	Artikel
Sprache:	eng
Schlagworte:	Anterior chamber Beta cells Calcium (intracellular) Calcium imaging Calcium signalling Diabetes mellitus Glucose Insulin secretion Labeling Secretion Transgenic mice
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