The effects of subtoxic dose of acetaminophen combined with exercise on the liver of rats

Regular physical exercise is beneficial to the body. Acute exercise causes oxidant stress in many tissues including the liver by creating an unbalanced status between oxidant and antioxidant levels. Analgesic drugs are commonly consumed to reduce the pain after exercise. Acetaminophen (APAP), common...

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Veröffentlicht in:	Physiological research 2023-07, Vol.72 (3), p.383-392
Hauptverfasser:	Aksu, I, Kiray, M, Gencoglu, C, Tas, A, Acikgoz, O
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetaminophen Acetaminophen - toxicity Analgesics Analgesics - metabolism Angiogenesis Animals Antioxidants Apoptosis Cell growth Chemical and Drug Induced Liver Injury - etiology Chemical and Drug Induced Liver Injury - metabolism Chemical and Drug Induced Liver Injury - prevention & control Drug dosages Enzymes Exercise Fitness equipment Health care Hepatotoxicity Inflammation Liver Liver - metabolism Male Metabolites Oxidants Oxidation Oxidative Stress Physical fitness Physiology Rats Rats, Wistar Running SIRT1 protein Sirtuin 1 - metabolism Toxicity Vascular endothelial growth factor Vascular Endothelial Growth Factor A - metabolism
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