SO2ClF-promoted chlorination-oxidation of 2-methylindoles: a one-step synthetic method to access 2,3-difunctionalized indoles

A direct and one-step method for the synthesis of 3-chloro-2-formylindoles with SO2ClF is reported. This tandem system consists of double electrophilic chlorination and deprotonation, nucleophilic addition of H2O to the resulting enamine intermediate, and subsequent oxidation. Various readily availa...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Organic chemistry frontiers an international journal of organic chemistry 2023-08, Vol.10 (16), p.4100-4104
Hauptverfasser:	Zheng, Yu, Ma, Tianting, Liu, Bingcong, Huang, Shenlin
Format:	Artikel
Sprache:	eng
Schlagworte:	Chlorination Indoles Organic chemistry Oxidation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!