Cobalt bis(dicarbollide) is a DNA-neutral pharmacophore

Cobalt bis(dicarbollide) (COSAN) is a metallacarborane used as a versatile pharmacophore to prepare biologically active hybrid organic-inorganic compounds or to improve the pharmacological properties of nucleosides, antisense oligonucleotides, and DNA intercalators. Despite these applications, COSAN...

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Veröffentlicht in:	Dalton transactions : an international journal of inorganic chemistry 2023-08, Vol.52 (3), p.1338-1347
Hauptverfasser:	Fink, Krzysztof, Cebula, Jakub, Tošner, Zden k, Psurski, Mateusz, Uchman, Mariusz, Goszczy ski, Tomasz M
Format:	Artikel
Sprache:	eng
Schlagworte:	Biocompatibility Cytotoxicity Dichroism Heat measurement Inorganic compounds NMR NMR spectroscopy Nuclear magnetic resonance Nuclear safety Nucleic acids Oligonucleotides Thermal denaturation Titration calorimetry Toxicity
Online-Zugang:	Volltext
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