Enantio‐ and Diastereoselective Synthesis of Chiral Tetrasubstituted α‐Amino Allenoates Bearing a Vicinal All‐Carbon Quaternary Stereocenter with Dual‐Copper‐Catalysis

The skeletons of chiral tetrasubstituted allenes bearing a vicinal all‐carbon quaternary stereocenter are of importance but still challenging to synthesize. Herein, we report enantio‐ and diastereoselective γ‐additions of 1‐alkynyl ketimines with dual‐copper‐catalysis under mild conditions, affordin...

Ausführliche Beschreibung