A treatment planning study comparison between supine and prone position for different lung tumour locations using CyberKnife TPS
Aim:CyberKnife is the most advanced form of stereotactic body radiotherapy (SBRT) system that uses a robotic arm to deliver highly focused beams of radiation; however, a limitation is that it only irradiates from ceiling to floor direction. In patients with posterior lungs tumour who are positioned...
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| Veröffentlicht in: | Journal of radiotherapy in practice 2022-09, Vol.21 (3), p.309-314 |
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| creator | Akasaka, Hiroaki Mizonobe, Kazufusa Oki, Yuya Uehara, Kazuyuki Harada, Aya Miyazaki, Shuichiro Kitatani, Keiji Yabuuchi, Tomonori Ishihara, Takeaki Miyawaki, Daisuke Nakayama, Masao Mukumoto, Naritoshi Yada, Ryuichi Nakaoka, Ai Kubota, Hikaru Kawaguchi, Hiroki Seno, Satoshi Sasaki, Ryohei Mayahara, Hiroshi |
| description | Aim:CyberKnife is the most advanced form of stereotactic body radiotherapy (SBRT) system that uses a robotic arm to deliver highly focused beams of radiation; however, a limitation is that it only irradiates from ceiling to floor direction. In patients with posterior lungs tumour who are positioned supine, normal lung tissue may suffer undesirable radiation injuries. This study compares the treatment planning between the prone set-up and the supine set-up for lung cancer in CyberKnife SBRT to decrease normal lung dose to avoid radiation side effects.Materials and methods:A human phantom was used to generate 108 plans (54 for prone and 54 for supine) using the CyberKnife planning platform. The supine and prone plans were compared in terms of the dosimetric characteristics, delivery efficiency and plan efficiency.Results:For posterior targets, the area of low-dose exposure to normal lungs was smaller in the prone set-up than in the supine set-up. V10 of the lungs was 7·53% and 10·47% (p < 0·001) in the anterior region, and 10·78% and 8·03% (p < 0·001) in the posterior region in the supine and prone set-up plans, respectively.Conclusions:The comparison between the prone set-up and the supine set-up was investigated with regard to target coverage and dose to organs at risk. Our results may be deployed in CyberKnife treatment planning to monitor normal tissue dose by considering patient positioning. This may assist in the design of better treatment plans and prevention of symptomatic radiation pneumonitis in lung cancer patients. |
| doi_str_mv | 10.1017/S1460396920001193 |
| format | Article |
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In patients with posterior lungs tumour who are positioned supine, normal lung tissue may suffer undesirable radiation injuries. This study compares the treatment planning between the prone set-up and the supine set-up for lung cancer in CyberKnife SBRT to decrease normal lung dose to avoid radiation side effects.Materials and methods:A human phantom was used to generate 108 plans (54 for prone and 54 for supine) using the CyberKnife planning platform. The supine and prone plans were compared in terms of the dosimetric characteristics, delivery efficiency and plan efficiency.Results:For posterior targets, the area of low-dose exposure to normal lungs was smaller in the prone set-up than in the supine set-up. V10 of the lungs was 7·53% and 10·47% (p < 0·001) in the anterior region, and 10·78% and 8·03% (p < 0·001) in the posterior region in the supine and prone set-up plans, respectively.Conclusions:The comparison between the prone set-up and the supine set-up was investigated with regard to target coverage and dose to organs at risk. Our results may be deployed in CyberKnife treatment planning to monitor normal tissue dose by considering patient positioning. This may assist in the design of better treatment plans and prevention of symptomatic radiation pneumonitis in lung cancer patients.</description><identifier>ISSN: 1460-3969</identifier><identifier>EISSN: 1467-1131</identifier><identifier>DOI: 10.1017/S1460396920001193</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Cancer therapies ; Conformity ; Dosimetry ; Ion beams ; Lung cancer ; Original Article ; Planning ; Pneumonitis ; Prone position ; Radiation ; Radiation dosage ; Radiation injuries ; Radiation therapy ; Robot arms ; Side effects ; Supine position ; Tumors</subject><ispartof>Journal of radiotherapy in practice, 2022-09, Vol.21 (3), p.309-314</ispartof><rights>The Author(s), 2021. Published by Cambridge University Press</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c317t-c46bc9c9022316b3afef5a75b424bb80f3e8e22adcdfcfe7cd10db6e86e0ebd83</citedby><cites>FETCH-LOGICAL-c317t-c46bc9c9022316b3afef5a75b424bb80f3e8e22adcdfcfe7cd10db6e86e0ebd83</cites><orcidid>0000-0003-1017-5229</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.cambridge.org/core/product/identifier/S1460396920001193/type/journal_article$$EHTML$$P50$$Gcambridge$$H</linktohtml><link.rule.ids>164,314,776,780,27903,27904,55606</link.rule.ids></links><search><creatorcontrib>Akasaka, Hiroaki</creatorcontrib><creatorcontrib>Mizonobe, Kazufusa</creatorcontrib><creatorcontrib>Oki, Yuya</creatorcontrib><creatorcontrib>Uehara, Kazuyuki</creatorcontrib><creatorcontrib>Harada, Aya</creatorcontrib><creatorcontrib>Miyazaki, Shuichiro</creatorcontrib><creatorcontrib>Kitatani, Keiji</creatorcontrib><creatorcontrib>Yabuuchi, Tomonori</creatorcontrib><creatorcontrib>Ishihara, Takeaki</creatorcontrib><creatorcontrib>Miyawaki, Daisuke</creatorcontrib><creatorcontrib>Nakayama, Masao</creatorcontrib><creatorcontrib>Mukumoto, Naritoshi</creatorcontrib><creatorcontrib>Yada, Ryuichi</creatorcontrib><creatorcontrib>Nakaoka, Ai</creatorcontrib><creatorcontrib>Kubota, Hikaru</creatorcontrib><creatorcontrib>Kawaguchi, Hiroki</creatorcontrib><creatorcontrib>Seno, Satoshi</creatorcontrib><creatorcontrib>Sasaki, Ryohei</creatorcontrib><creatorcontrib>Mayahara, Hiroshi</creatorcontrib><title>A treatment planning study comparison between supine and prone position for different lung tumour locations using CyberKnife TPS</title><title>Journal of radiotherapy in practice</title><addtitle>J Radiother Pract</addtitle><description>Aim:CyberKnife is the most advanced form of stereotactic body radiotherapy (SBRT) system that uses a robotic arm to deliver highly focused beams of radiation; however, a limitation is that it only irradiates from ceiling to floor direction. In patients with posterior lungs tumour who are positioned supine, normal lung tissue may suffer undesirable radiation injuries. This study compares the treatment planning between the prone set-up and the supine set-up for lung cancer in CyberKnife SBRT to decrease normal lung dose to avoid radiation side effects.Materials and methods:A human phantom was used to generate 108 plans (54 for prone and 54 for supine) using the CyberKnife planning platform. The supine and prone plans were compared in terms of the dosimetric characteristics, delivery efficiency and plan efficiency.Results:For posterior targets, the area of low-dose exposure to normal lungs was smaller in the prone set-up than in the supine set-up. V10 of the lungs was 7·53% and 10·47% (p < 0·001) in the anterior region, and 10·78% and 8·03% (p < 0·001) in the posterior region in the supine and prone set-up plans, respectively.Conclusions:The comparison between the prone set-up and the supine set-up was investigated with regard to target coverage and dose to organs at risk. Our results may be deployed in CyberKnife treatment planning to monitor normal tissue dose by considering patient positioning. This may assist in the design of better treatment plans and prevention of symptomatic radiation pneumonitis in lung cancer patients.</description><subject>Cancer therapies</subject><subject>Conformity</subject><subject>Dosimetry</subject><subject>Ion beams</subject><subject>Lung cancer</subject><subject>Original Article</subject><subject>Planning</subject><subject>Pneumonitis</subject><subject>Prone position</subject><subject>Radiation</subject><subject>Radiation dosage</subject><subject>Radiation injuries</subject><subject>Radiation therapy</subject><subject>Robot arms</subject><subject>Side effects</subject><subject>Supine 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injuries</topic><topic>Radiation therapy</topic><topic>Robot arms</topic><topic>Side effects</topic><topic>Supine position</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Akasaka, Hiroaki</creatorcontrib><creatorcontrib>Mizonobe, Kazufusa</creatorcontrib><creatorcontrib>Oki, Yuya</creatorcontrib><creatorcontrib>Uehara, Kazuyuki</creatorcontrib><creatorcontrib>Harada, Aya</creatorcontrib><creatorcontrib>Miyazaki, Shuichiro</creatorcontrib><creatorcontrib>Kitatani, Keiji</creatorcontrib><creatorcontrib>Yabuuchi, Tomonori</creatorcontrib><creatorcontrib>Ishihara, Takeaki</creatorcontrib><creatorcontrib>Miyawaki, Daisuke</creatorcontrib><creatorcontrib>Nakayama, Masao</creatorcontrib><creatorcontrib>Mukumoto, Naritoshi</creatorcontrib><creatorcontrib>Yada, Ryuichi</creatorcontrib><creatorcontrib>Nakaoka, Ai</creatorcontrib><creatorcontrib>Kubota, Hikaru</creatorcontrib><creatorcontrib>Kawaguchi, 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Hiroki</au><au>Seno, Satoshi</au><au>Sasaki, Ryohei</au><au>Mayahara, Hiroshi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A treatment planning study comparison between supine and prone position for different lung tumour locations using CyberKnife TPS</atitle><jtitle>Journal of radiotherapy in practice</jtitle><addtitle>J Radiother Pract</addtitle><date>2022-09-01</date><risdate>2022</risdate><volume>21</volume><issue>3</issue><spage>309</spage><epage>314</epage><pages>309-314</pages><issn>1460-3969</issn><eissn>1467-1131</eissn><abstract>Aim:CyberKnife is the most advanced form of stereotactic body radiotherapy (SBRT) system that uses a robotic arm to deliver highly focused beams of radiation; however, a limitation is that it only irradiates from ceiling to floor direction. In patients with posterior lungs tumour who are positioned supine, normal lung tissue may suffer undesirable radiation injuries. This study compares the treatment planning between the prone set-up and the supine set-up for lung cancer in CyberKnife SBRT to decrease normal lung dose to avoid radiation side effects.Materials and methods:A human phantom was used to generate 108 plans (54 for prone and 54 for supine) using the CyberKnife planning platform. The supine and prone plans were compared in terms of the dosimetric characteristics, delivery efficiency and plan efficiency.Results:For posterior targets, the area of low-dose exposure to normal lungs was smaller in the prone set-up than in the supine set-up. V10 of the lungs was 7·53% and 10·47% (p < 0·001) in the anterior region, and 10·78% and 8·03% (p < 0·001) in the posterior region in the supine and prone set-up plans, respectively.Conclusions:The comparison between the prone set-up and the supine set-up was investigated with regard to target coverage and dose to organs at risk. Our results may be deployed in CyberKnife treatment planning to monitor normal tissue dose by considering patient positioning. This may assist in the design of better treatment plans and prevention of symptomatic radiation pneumonitis in lung cancer patients.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><doi>10.1017/S1460396920001193</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0003-1017-5229</orcidid></addata></record> |
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| ispartof | Journal of radiotherapy in practice, 2022-09, Vol.21 (3), p.309-314 |
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| source | Cambridge University Press Journals Complete |
| subjects | Cancer therapies Conformity Dosimetry Ion beams Lung cancer Original Article Planning Pneumonitis Prone position Radiation Radiation dosage Radiation injuries Radiation therapy Robot arms Side effects Supine position Tumors |
| title | A treatment planning study comparison between supine and prone position for different lung tumour locations using CyberKnife TPS |
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