Investigation of HER2 I655V and PHB 3′UTR C > T polymorphisms in azoospermic infertile males

Background Male infertility is a complex, multifactorial pathological condition with a highly heterogeneous phenotypic variation, from complete absence of spermatozoa in the testicles (azoospermia) to marked changes in sperm quality. The Erb-B2 receptor tyrosine kinase 2 gene ( ERBB2 , also often ca...

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Veröffentlicht in:	Egyptian Journal of Medical Human Genetics 2023-12, Vol.24 (1), p.43-6, Article 43
Hauptverfasser:	Yildiz, Irem, Karakus, Nevin, Erdemir, Fikret
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated regions Azoospermia Chemotherapy DNA polymerase Epidermal growth factor Erb-B2 receptor tyrosine kinase 2 ErbB-2 protein Gene polymorphism Genotype & phenotype Infertility Kinases Males Medicine Medicine & Public Health Membrane potential Motility Patients Peripheral blood Phenotypic variations Polymorphism Prohibitin Protein-tyrosine kinase receptors Reactive oxygen species Restriction fragment length polymorphism Sperm Spermatogenesis Statistical analysis Steroidogenesis Testes Urology Variance analysis Y chromosomes
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