488 GNUV201, a novel human and mouse cross-reactive PD-1 monoclonal antibody for cancer immunotherapy

BackgroundSeveral PD-1 antibodies have been approved as anti-cancer therapies which work by blocking the interaction of PD-1 with its ligand PD-L1, thus restoring anti-cancer T cell activities. However, cross-reactive anti-PD-1 antibodies binding to both human and pre-clinically relevant animal mode...

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Veröffentlicht in:Journal for immunotherapy of cancer 2022-11, Vol.10 (Suppl 2), p.A509-A509
Hauptverfasser: Kim, Haemi, Kyoung-Jin, Kim, Myeong Jin Yoon, Choih, Jenny, Eun Ji Cho, Hak-Jun, Jung, Lee, Kwanghyun, Kim, Jayoung, Park, Chae Gyu, Han, Sungho, Bae, Donggoo, Park, Heungrok
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Sprache:eng
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