Are Clinical Predictors of Oral Malignancy Risk Changing? A Sample Study
Objective: Our study assesss the clinical features of oral lesions that require histological examination and patient-reported symptoms to estimate the risk of malignancy and to determine the presence of any altered features. Materials and Methods: Demographic characteristics of 70 patients and clini...
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| Veröffentlicht in: | Meandros medical and dental journal 2022-06, Vol.23 (2), p.175-181 |
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| container_title | Meandros medical and dental journal |
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| creator | Özer, Nezaket Ezgi Karaca, Betül Gürhan, Ceyda Boyacıoğlu, Hayal Aykutlu, Umut Güneri, Pelin |
| description | Objective: Our study assesss the clinical features of oral lesions that require histological examination and patient-reported symptoms to estimate the risk of malignancy and to determine the presence of any altered features. Materials and Methods: Demographic characteristics of 70 patients and clinical features of lesions were analyzed using chi-square test, Fisher’s Exact test of Independence and discriminant function analysis. Results: Margins, lymphadenopathy, patient’s self-awareness of the lesion associated with mass effect, surface texture, colour, ulceration, loss of function and pain were significant parameters indicating the risk of malignancy (p |
| doi_str_mv | 10.4274/meandros.galenos.2021.16046 |
| format | Article |
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A Sample Study</title><source>Alma/SFX Local Collection</source><creator>Özer, Nezaket Ezgi ; Karaca, Betül ; Gürhan, Ceyda ; Boyacıoğlu, Hayal ; Aykutlu, Umut ; Güneri, Pelin</creator><creatorcontrib>Özer, Nezaket Ezgi ; Karaca, Betül ; Gürhan, Ceyda ; Boyacıoğlu, Hayal ; Aykutlu, Umut ; Güneri, Pelin</creatorcontrib><description>Objective: Our study assesss the clinical features of oral lesions that require histological examination and patient-reported symptoms to estimate the risk of malignancy and to determine the presence of any altered features. Materials and Methods: Demographic characteristics of 70 patients and clinical features of lesions were analyzed using chi-square test, Fisher’s Exact test of Independence and discriminant function analysis. Results: Margins, lymphadenopathy, patient’s self-awareness of the lesion associated with mass effect, surface texture, colour, ulceration, loss of function and pain were significant parameters indicating the risk of malignancy (p<0.05). Analyses of the parameters related to the high risk of malignancy have led to a statistical model for clinical differentiation of benign lesions from malignancies with an accuracy of 91.4% (p=0.016). The statistical model demonstrated that the most important discriminative features were margins, surface texture, patient’s self-awareness, lymphadenopathy, loss of function, ulceration, colour, and pain, respectively. Conclusion: In our study, age, gender, duration and localization did not anticipate the nature of the lesion. Our statistical model showed that irregular/indistinct margins and surface textures and the presence of lymphadenopathy have a higher risk of malignancy.</description><identifier>ISSN: 2149-9063</identifier><identifier>EISSN: 2149-9063</identifier><identifier>DOI: 10.4274/meandros.galenos.2021.16046</identifier><language>eng</language><publisher>Aydın: Galenos Publishing House</publisher><subject>Biopsy ; Lesions ; Localization ; Lymphadenopathy ; Malignancy ; Mathematical models ; Medical prognosis ; Medical screening ; Oral cancer ; Pain ; Patients ; Self awareness ; Self-recognition ; Statistical analysis ; Ulcers</subject><ispartof>Meandros medical and dental journal, 2022-06, Vol.23 (2), p.175-181</ispartof><rights>2022. This work is published under https://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c218t-e7e22f419b96e3a4bceeb71b06d8dd9692f2e1f9ebe84e1b4fe2b7eafa927dd63</cites><orcidid>0000-0003-0887-0302 ; 0000-0001-9423-9191 ; 0000-0002-5733-0954 ; 0000-0003-3123-3272 ; 0000-0002-4101-4965 ; 0000-0002-9373-0912</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Özer, Nezaket Ezgi</creatorcontrib><creatorcontrib>Karaca, Betül</creatorcontrib><creatorcontrib>Gürhan, Ceyda</creatorcontrib><creatorcontrib>Boyacıoğlu, Hayal</creatorcontrib><creatorcontrib>Aykutlu, Umut</creatorcontrib><creatorcontrib>Güneri, Pelin</creatorcontrib><title>Are Clinical Predictors of Oral Malignancy Risk Changing? 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A Sample Study</atitle><jtitle>Meandros medical and dental journal</jtitle><date>2022-06-01</date><risdate>2022</risdate><volume>23</volume><issue>2</issue><spage>175</spage><epage>181</epage><pages>175-181</pages><issn>2149-9063</issn><eissn>2149-9063</eissn><abstract>Objective: Our study assesss the clinical features of oral lesions that require histological examination and patient-reported symptoms to estimate the risk of malignancy and to determine the presence of any altered features. Materials and Methods: Demographic characteristics of 70 patients and clinical features of lesions were analyzed using chi-square test, Fisher’s Exact test of Independence and discriminant function analysis. Results: Margins, lymphadenopathy, patient’s self-awareness of the lesion associated with mass effect, surface texture, colour, ulceration, loss of function and pain were significant parameters indicating the risk of malignancy (p<0.05). Analyses of the parameters related to the high risk of malignancy have led to a statistical model for clinical differentiation of benign lesions from malignancies with an accuracy of 91.4% (p=0.016). The statistical model demonstrated that the most important discriminative features were margins, surface texture, patient’s self-awareness, lymphadenopathy, loss of function, ulceration, colour, and pain, respectively. Conclusion: In our study, age, gender, duration and localization did not anticipate the nature of the lesion. 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| source | Alma/SFX Local Collection |
| subjects | Biopsy Lesions Localization Lymphadenopathy Malignancy Mathematical models Medical prognosis Medical screening Oral cancer Pain Patients Self awareness Self-recognition Statistical analysis Ulcers |
| title | Are Clinical Predictors of Oral Malignancy Risk Changing? A Sample Study |
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