Effects of Polyphenols on changes in the transport of Ca2+ NMDA-receptors under the influence of L-glutamate

Increasing amount of evidence suggests that age-related dysregulation of neuronal Ca2+ homeostasis may play a proximal role in the pathogenesis of Alzheimer's disease, as impaired Ca2+ can cause synaptic deficits and contribute to the accumulation of Aβ plaques and neurofibrillary tangles.Ca2+...

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Veröffentlicht in:	Research journal of pharmacy and technology 2023-03, Vol.16 (3), p.1205-1213
Hauptverfasser:	Khoshimov, Nozim N, Mukhtorov, Alisher A, Nasirov, Kabil E, Rakhimov, Rakhmatilla N, Mamadaminov, Rahmatjon R
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Apoptosis Drugs Endoplasmic reticulum Homeostasis Membranes Mitochondria Neurodegeneration Neurons Pathogenesis Pathology Plasma Polyphenols Proteins
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