RP-HPLC hyphenated with ESI -Q-TOF –MS for the detection of potential degradants in dolutegravir

Dolutegravir is an antiviral agent, a second-generation HIV integrase strand transfer inhibitor (INSTI). A precise liquid chromatography-tandem mass spectrometry method has been developed and validated for the detection of potential degradants in Dolutegravir. The goal of this study was to detect ma...

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Veröffentlicht in:	Research journal of pharmacy and technology 2023-03, Vol.16 (3), p.1012-1016
Hauptverfasser:	Mathew, Jane, Mathew V, Neethu
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Antiretroviral drugs Chromatography Ions Mass spectrometry Oxidation Scientific imaging
Online-Zugang:	Volltext
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