A tetrahydroacridine derivative and its conjugate with gold nanoparticles: promising agents for the treatment of Alzheimer's disease

A new tetrahydroacridine derivative (CHDA) with acetylcholinesterase inhibitory properties was synthesized. Using a range of physicochemical techniques, it was shown that the compound strongly adsorbs onto the surface of planar macroscopic or nanoparticulate gold, forming a nearly full monolayer. Th...

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Veröffentlicht in:	Physical chemistry chemical physics : PCCP 2023-06, Vol.25 (25), p.16796-1686
Hauptverfasser:	Mojzych, Ilona, Zawadzka, Anna, Kaczy ska, Katarzyna, Wojciechowski, Piotr, Zaj c, Dominika, Chotkowski, Maciej, Wiktorska, Katarzyna, Maurin, Jan K, Mazur, Maciej
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Conjugates Conjugation Electrochemical analysis Gold Health services Medical imaging Nanoparticles
Online-Zugang:	Volltext
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