Antioxidant, antimicrobial, and cytotoxic potential of Euphorbia royleana extract-mediated silver and copper oxide nanoparticles
The present research demonstrates the first-time successful synthesis of silver nanoparticles (Ag NPs) and copper oxide nanoparticles (Cu 2 O NPs) from Euphorbia royleana pulp extract. The morphological features of synthesized NPs were examined using XRD, FTIR, FE-SEM, and TEM. With the presence of...
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| Veröffentlicht in: | Chemical papers 2023-08, Vol.77 (8), p.4643-4657 |
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| creator | Kumari, Amita Naveen Dhatwalia, Jyoti Thakur, Shabnam Radhakrishnan, Arunkumar Chauhan, Ankush Chandan, Gourav Choi, Byung Hyune Neetika Nidhi |
| description | The present research demonstrates the first-time successful synthesis of silver nanoparticles (Ag NPs) and copper oxide nanoparticles (Cu
2
O NPs) from
Euphorbia royleana
pulp extract. The morphological features of synthesized NPs were examined using XRD, FTIR, FE-SEM, and TEM. With the presence of surface-bonded phenolic groups, the particle size of Ag NPs and Cu
2
O NPs (spherical) was revealed to be 20.53 ± 1.15 nm and 3.06 ± 0.04 nm, respectively. The DPPH and FRAP assays demonstrated significant antioxidant activity (Ag NPs: 60.44 µg/mL and 141.86 µg/mL; Cu
2
O NPs: 63.55 µg/mL and 138.9 µg/mL, respectively). Additionally, Ag and Cu
2
O NPs showed good antimicrobial activity (31.25 to 500 µg/mL) against
Bacillus subtilis
,
Staphylococcus aureus
,
Klebsiella pneumoniae
,
Escherichia coli
,
Pseudomonas aeruginosa
,
Fusarium oxysporum,
and
Rosellinia necatrix.
Against colon cancer cell lines, nanoparticles showed potent cytotoxic activity (IC
50
-50.12 µg/mL for Ag NPs and 61.93 µg/mL for Cu
2
O NPs). As a result of their significant biological activities, the synthesized NPs showed potency to be utilized in various biomedical applications after in vivo studies. |
| doi_str_mv | 10.1007/s11696-023-02814-3 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2828399276</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2828399276</sourcerecordid><originalsourceid>FETCH-LOGICAL-c319t-2cc52f692126bd7249f6de6efbda5bada7e34c6612d9874bab0e99060d0f760a3</originalsourceid><addsrcrecordid>eNp9kEtLxDAYRYMoOI7-AVcBt1bzaNNmOQzjAwQ3ug5fk1QzdJqaZGRm5083YwV3LvIi594PDkKXlNxQQurbSKmQoiCM59XQsuBHaEY5F4UkdXWMZoQLUQhesVN0FuOakLIkFZmhr8WQnN85A0O6xnlzG6eDbx30h6fBep98yoDGo082_0OPfYdX2_Hdh4zh4Pe9hQGw3aUAOhUbaxwka3B0_acNU4sfx3w9DLJ4gMGPEJLTvY3n6KSDPtqL33OOXu9WL8uH4un5_nG5eCo0pzIVTOuKdUIyykRralbKThgrbNcaqFowUFteaiEoM7KpyxZaYqUkghjS1YIAn6OrqXcM_mNrY1Jrvw1DHqlYwxouJatFpthEZQcxBtupMbgNhL2iRB1Mq8m0yqbVj2nFc4hPoZjh4c2Gv-p_Ut_jxoSO</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2828399276</pqid></control><display><type>article</type><title>Antioxidant, antimicrobial, and cytotoxic potential of Euphorbia royleana extract-mediated silver and copper oxide nanoparticles</title><source>SpringerLink Journals - AutoHoldings</source><creator>Kumari, Amita ; Naveen ; Dhatwalia, Jyoti ; Thakur, Shabnam ; Radhakrishnan, Arunkumar ; Chauhan, Ankush ; Chandan, Gourav ; Choi, Byung Hyune ; Neetika ; Nidhi</creator><creatorcontrib>Kumari, Amita ; Naveen ; Dhatwalia, Jyoti ; Thakur, Shabnam ; Radhakrishnan, Arunkumar ; Chauhan, Ankush ; Chandan, Gourav ; Choi, Byung Hyune ; Neetika ; Nidhi</creatorcontrib><description>The present research demonstrates the first-time successful synthesis of silver nanoparticles (Ag NPs) and copper oxide nanoparticles (Cu
2
O NPs) from
Euphorbia royleana
pulp extract. The morphological features of synthesized NPs were examined using XRD, FTIR, FE-SEM, and TEM. With the presence of surface-bonded phenolic groups, the particle size of Ag NPs and Cu
2
O NPs (spherical) was revealed to be 20.53 ± 1.15 nm and 3.06 ± 0.04 nm, respectively. The DPPH and FRAP assays demonstrated significant antioxidant activity (Ag NPs: 60.44 µg/mL and 141.86 µg/mL; Cu
2
O NPs: 63.55 µg/mL and 138.9 µg/mL, respectively). Additionally, Ag and Cu
2
O NPs showed good antimicrobial activity (31.25 to 500 µg/mL) against
Bacillus subtilis
,
Staphylococcus aureus
,
Klebsiella pneumoniae
,
Escherichia coli
,
Pseudomonas aeruginosa
,
Fusarium oxysporum,
and
Rosellinia necatrix.
Against colon cancer cell lines, nanoparticles showed potent cytotoxic activity (IC
50
-50.12 µg/mL for Ag NPs and 61.93 µg/mL for Cu
2
O NPs). As a result of their significant biological activities, the synthesized NPs showed potency to be utilized in various biomedical applications after in vivo studies.</description><identifier>ISSN: 0366-6352</identifier><identifier>EISSN: 1336-9075</identifier><identifier>EISSN: 2585-7290</identifier><identifier>DOI: 10.1007/s11696-023-02814-3</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Antiinfectives and antibacterials ; Antimicrobial agents ; Antioxidants ; Biochemistry ; Biological effects ; Biomedical materials ; Biotechnology ; Chemistry ; Chemistry and Materials Science ; Chemistry/Food Science ; Copper oxides ; Cytotoxicity ; E coli ; Fusarium oxysporum ; In vivo methods and tests ; Industrial Chemistry/Chemical Engineering ; Klebsiella ; Materials Science ; Medicinal Chemistry ; Nanoparticles ; Original Paper ; Silver ; Synthesis</subject><ispartof>Chemical papers, 2023-08, Vol.77 (8), p.4643-4657</ispartof><rights>Institute of Chemistry, Slovak Academy of Sciences 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c319t-2cc52f692126bd7249f6de6efbda5bada7e34c6612d9874bab0e99060d0f760a3</citedby><cites>FETCH-LOGICAL-c319t-2cc52f692126bd7249f6de6efbda5bada7e34c6612d9874bab0e99060d0f760a3</cites><orcidid>0000-0001-7707-1032</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11696-023-02814-3$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11696-023-02814-3$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27923,27924,41487,42556,51318</link.rule.ids></links><search><creatorcontrib>Kumari, Amita</creatorcontrib><creatorcontrib>Naveen</creatorcontrib><creatorcontrib>Dhatwalia, Jyoti</creatorcontrib><creatorcontrib>Thakur, Shabnam</creatorcontrib><creatorcontrib>Radhakrishnan, Arunkumar</creatorcontrib><creatorcontrib>Chauhan, Ankush</creatorcontrib><creatorcontrib>Chandan, Gourav</creatorcontrib><creatorcontrib>Choi, Byung Hyune</creatorcontrib><creatorcontrib>Neetika</creatorcontrib><creatorcontrib>Nidhi</creatorcontrib><title>Antioxidant, antimicrobial, and cytotoxic potential of Euphorbia royleana extract-mediated silver and copper oxide nanoparticles</title><title>Chemical papers</title><addtitle>Chem. Pap</addtitle><description>The present research demonstrates the first-time successful synthesis of silver nanoparticles (Ag NPs) and copper oxide nanoparticles (Cu
2
O NPs) from
Euphorbia royleana
pulp extract. The morphological features of synthesized NPs were examined using XRD, FTIR, FE-SEM, and TEM. With the presence of surface-bonded phenolic groups, the particle size of Ag NPs and Cu
2
O NPs (spherical) was revealed to be 20.53 ± 1.15 nm and 3.06 ± 0.04 nm, respectively. The DPPH and FRAP assays demonstrated significant antioxidant activity (Ag NPs: 60.44 µg/mL and 141.86 µg/mL; Cu
2
O NPs: 63.55 µg/mL and 138.9 µg/mL, respectively). Additionally, Ag and Cu
2
O NPs showed good antimicrobial activity (31.25 to 500 µg/mL) against
Bacillus subtilis
,
Staphylococcus aureus
,
Klebsiella pneumoniae
,
Escherichia coli
,
Pseudomonas aeruginosa
,
Fusarium oxysporum,
and
Rosellinia necatrix.
Against colon cancer cell lines, nanoparticles showed potent cytotoxic activity (IC
50
-50.12 µg/mL for Ag NPs and 61.93 µg/mL for Cu
2
O NPs). As a result of their significant biological activities, the synthesized NPs showed potency to be utilized in various biomedical applications after in vivo studies.</description><subject>Antiinfectives and antibacterials</subject><subject>Antimicrobial agents</subject><subject>Antioxidants</subject><subject>Biochemistry</subject><subject>Biological effects</subject><subject>Biomedical materials</subject><subject>Biotechnology</subject><subject>Chemistry</subject><subject>Chemistry and Materials Science</subject><subject>Chemistry/Food Science</subject><subject>Copper oxides</subject><subject>Cytotoxicity</subject><subject>E coli</subject><subject>Fusarium oxysporum</subject><subject>In vivo methods and tests</subject><subject>Industrial Chemistry/Chemical Engineering</subject><subject>Klebsiella</subject><subject>Materials Science</subject><subject>Medicinal Chemistry</subject><subject>Nanoparticles</subject><subject>Original Paper</subject><subject>Silver</subject><subject>Synthesis</subject><issn>0366-6352</issn><issn>1336-9075</issn><issn>2585-7290</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNp9kEtLxDAYRYMoOI7-AVcBt1bzaNNmOQzjAwQ3ug5fk1QzdJqaZGRm5083YwV3LvIi594PDkKXlNxQQurbSKmQoiCM59XQsuBHaEY5F4UkdXWMZoQLUQhesVN0FuOakLIkFZmhr8WQnN85A0O6xnlzG6eDbx30h6fBep98yoDGo082_0OPfYdX2_Hdh4zh4Pe9hQGw3aUAOhUbaxwka3B0_acNU4sfx3w9DLJ4gMGPEJLTvY3n6KSDPtqL33OOXu9WL8uH4un5_nG5eCo0pzIVTOuKdUIyykRralbKThgrbNcaqFowUFteaiEoM7KpyxZaYqUkghjS1YIAn6OrqXcM_mNrY1Jrvw1DHqlYwxouJatFpthEZQcxBtupMbgNhL2iRB1Mq8m0yqbVj2nFc4hPoZjh4c2Gv-p_Ut_jxoSO</recordid><startdate>20230801</startdate><enddate>20230801</enddate><creator>Kumari, Amita</creator><creator>Naveen</creator><creator>Dhatwalia, Jyoti</creator><creator>Thakur, Shabnam</creator><creator>Radhakrishnan, Arunkumar</creator><creator>Chauhan, Ankush</creator><creator>Chandan, Gourav</creator><creator>Choi, Byung Hyune</creator><creator>Neetika</creator><creator>Nidhi</creator><general>Springer International Publishing</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>L7M</scope><orcidid>https://orcid.org/0000-0001-7707-1032</orcidid></search><sort><creationdate>20230801</creationdate><title>Antioxidant, antimicrobial, and cytotoxic potential of Euphorbia royleana extract-mediated silver and copper oxide nanoparticles</title><author>Kumari, Amita ; Naveen ; Dhatwalia, Jyoti ; Thakur, Shabnam ; Radhakrishnan, Arunkumar ; Chauhan, Ankush ; Chandan, Gourav ; Choi, Byung Hyune ; Neetika ; Nidhi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c319t-2cc52f692126bd7249f6de6efbda5bada7e34c6612d9874bab0e99060d0f760a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Antiinfectives and antibacterials</topic><topic>Antimicrobial agents</topic><topic>Antioxidants</topic><topic>Biochemistry</topic><topic>Biological effects</topic><topic>Biomedical materials</topic><topic>Biotechnology</topic><topic>Chemistry</topic><topic>Chemistry and Materials Science</topic><topic>Chemistry/Food Science</topic><topic>Copper oxides</topic><topic>Cytotoxicity</topic><topic>E coli</topic><topic>Fusarium oxysporum</topic><topic>In vivo methods and tests</topic><topic>Industrial Chemistry/Chemical Engineering</topic><topic>Klebsiella</topic><topic>Materials Science</topic><topic>Medicinal Chemistry</topic><topic>Nanoparticles</topic><topic>Original Paper</topic><topic>Silver</topic><topic>Synthesis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kumari, Amita</creatorcontrib><creatorcontrib>Naveen</creatorcontrib><creatorcontrib>Dhatwalia, Jyoti</creatorcontrib><creatorcontrib>Thakur, Shabnam</creatorcontrib><creatorcontrib>Radhakrishnan, Arunkumar</creatorcontrib><creatorcontrib>Chauhan, Ankush</creatorcontrib><creatorcontrib>Chandan, Gourav</creatorcontrib><creatorcontrib>Choi, Byung Hyune</creatorcontrib><creatorcontrib>Neetika</creatorcontrib><creatorcontrib>Nidhi</creatorcontrib><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Chemical papers</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kumari, Amita</au><au>Naveen</au><au>Dhatwalia, Jyoti</au><au>Thakur, Shabnam</au><au>Radhakrishnan, Arunkumar</au><au>Chauhan, Ankush</au><au>Chandan, Gourav</au><au>Choi, Byung Hyune</au><au>Neetika</au><au>Nidhi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antioxidant, antimicrobial, and cytotoxic potential of Euphorbia royleana extract-mediated silver and copper oxide nanoparticles</atitle><jtitle>Chemical papers</jtitle><stitle>Chem. Pap</stitle><date>2023-08-01</date><risdate>2023</risdate><volume>77</volume><issue>8</issue><spage>4643</spage><epage>4657</epage><pages>4643-4657</pages><issn>0366-6352</issn><eissn>1336-9075</eissn><eissn>2585-7290</eissn><abstract>The present research demonstrates the first-time successful synthesis of silver nanoparticles (Ag NPs) and copper oxide nanoparticles (Cu
2
O NPs) from
Euphorbia royleana
pulp extract. The morphological features of synthesized NPs were examined using XRD, FTIR, FE-SEM, and TEM. With the presence of surface-bonded phenolic groups, the particle size of Ag NPs and Cu
2
O NPs (spherical) was revealed to be 20.53 ± 1.15 nm and 3.06 ± 0.04 nm, respectively. The DPPH and FRAP assays demonstrated significant antioxidant activity (Ag NPs: 60.44 µg/mL and 141.86 µg/mL; Cu
2
O NPs: 63.55 µg/mL and 138.9 µg/mL, respectively). Additionally, Ag and Cu
2
O NPs showed good antimicrobial activity (31.25 to 500 µg/mL) against
Bacillus subtilis
,
Staphylococcus aureus
,
Klebsiella pneumoniae
,
Escherichia coli
,
Pseudomonas aeruginosa
,
Fusarium oxysporum,
and
Rosellinia necatrix.
Against colon cancer cell lines, nanoparticles showed potent cytotoxic activity (IC
50
-50.12 µg/mL for Ag NPs and 61.93 µg/mL for Cu
2
O NPs). As a result of their significant biological activities, the synthesized NPs showed potency to be utilized in various biomedical applications after in vivo studies.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><doi>10.1007/s11696-023-02814-3</doi><tpages>15</tpages><orcidid>https://orcid.org/0000-0001-7707-1032</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0366-6352 |
| ispartof | Chemical papers, 2023-08, Vol.77 (8), p.4643-4657 |
| issn | 0366-6352 1336-9075 2585-7290 |
| language | eng |
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| subjects | Antiinfectives and antibacterials Antimicrobial agents Antioxidants Biochemistry Biological effects Biomedical materials Biotechnology Chemistry Chemistry and Materials Science Chemistry/Food Science Copper oxides Cytotoxicity E coli Fusarium oxysporum In vivo methods and tests Industrial Chemistry/Chemical Engineering Klebsiella Materials Science Medicinal Chemistry Nanoparticles Original Paper Silver Synthesis |
| title | Antioxidant, antimicrobial, and cytotoxic potential of Euphorbia royleana extract-mediated silver and copper oxide nanoparticles |
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