Effect of Pre and Post-Surgical Correction of Left Displacement Abomasum on Oxidative Stress, Metabolic Status and Hematological Profile Changes in Serum of Dairy Cows of Pakistan
ABSTRACT This study was aimed to evaluate the oxidative stress status (malondialdehyde, MDA; catalase, CAT), metabolic status (beta hydroxybutyric acid, BHBA; nonesterified fatty acid NEFA) and hematological changes (hemoglobin, total leucocytes, red blood cells, neutrophils, platelets, lymphocytes)...
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| Veröffentlicht in: | Pakistan journal of zoology 2023-08, Vol.55 (4), p.1755 |
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| creator | Rizwan, Muhammad Akbar, Hamid Anjum, Aftab Ahmad Khan, Muhammad Arif Durrani, Aneela Zameer Hayat, Muhammad Abid Masood, Anjum Sajjad, Muhammad Talha Raza, Nadeem |
| description | ABSTRACT This study was aimed to evaluate the oxidative stress status (malondialdehyde, MDA; catalase, CAT), metabolic status (beta hydroxybutyric acid, BHBA; nonesterified fatty acid NEFA) and hematological changes (hemoglobin, total leucocytes, red blood cells, neutrophils, platelets, lymphocytes) in serum of dairy cows before and after the surgical correction of left displacement abomasum. Twenty-six cows were divided into two groups as control (Group-A) and treatment (Group-B), each of 13 cows. Left displacement abomasum was confirmed by clinical assessment and ultrasonography, and then was surgically treated through Dirksen technique. Blood samples of both groups were collected on days 0, 7, 14, 21, and 28. Levels of various oxidative, metabolic and hematological parameters were measured by authenticated standard methods. We observed that serum levels of MDA and BHBA were higher at day 0 to day 14 (P |
| doi_str_mv | 10.17582/journal.pjz/20220221120204 |
| format | Article |
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Twenty-six cows were divided into two groups as control (Group-A) and treatment (Group-B), each of 13 cows. Left displacement abomasum was confirmed by clinical assessment and ultrasonography, and then was surgically treated through Dirksen technique. Blood samples of both groups were collected on days 0, 7, 14, 21, and 28. Levels of various oxidative, metabolic and hematological parameters were measured by authenticated standard methods. We observed that serum levels of MDA and BHBA were higher at day 0 to day 14 (P<0.01), while the level of nonesterified fatty acid (NEFA) was higher at day 0 to day 7 (P<0.01) which dropped down to normal at day 21 (P>0.05) post-surgery in Group-B than Group-A. Moreover, CAT level in serum decreased (P<0.01) at day 0 to day 7, then it gradually increased to normal on day 14 to day 21 (P>0.05) post-surgery in Group B compared to Group A. In addition, levels of hemoglobin, total leucocytes, neutrophils were higher at day 0 to day 7 (P<0.01), while red blood cells and lymphocytes were lower at day 0 to day 14 (P<0.01) which became normal at day 28 (P>0.05) in Group-B than Group-A. The level of platelets was higher at day 0 (P<0.01), then gradually decreased to normal at day 28 in Group-B than Group-A. In conclusion, left displacement abomasum is associated with metabolic, oxidative and hematological disturbances which can be rectified through surgical correction. However, it is recommended to provide antioxidant therapy in adjunct with surgical correction for early recovery.]]></description><identifier>ISSN: 0030-9923</identifier><identifier>EISSN: 0030-9923</identifier><identifier>DOI: 10.17582/journal.pjz/20220221120204</identifier><language>eng</language><publisher>Lahore: Knowledge Bylanes</publisher><subject>Abdomen ; Abomasum ; Animals ; Anorexia ; Auscultation ; Catalase ; Cattle ; Cytokines ; Dairy cattle ; Dairy farms ; Diseases ; Diseases and pests ; Erythrocytes ; Fatty acids ; Health aspects ; Hematology ; Hemoglobin ; Laboratories ; Leukocytes ; Leukocytes (neutrophilic) ; Lipid peroxidation ; Lipids ; Lymphocytes ; Metabolism ; Milk ; Motility ; Neutrophils ; Oxidation ; Oxidative stress ; Platelets ; Serum levels ; Stress analysis ; Surgery ; Ultrasonic imaging</subject><ispartof>Pakistan journal of zoology, 2023-08, Vol.55 (4), p.1755</ispartof><rights>COPYRIGHT 2023 Knowledge Bylanes</rights><rights>(c)2023 Pakistan Journal of Zoology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c385t-785ba6febc8aa9cd4a8e6421fd4af69b816f3a6a096500e218c66ea84a270e293</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Rizwan, Muhammad</creatorcontrib><creatorcontrib>Akbar, Hamid</creatorcontrib><creatorcontrib>Anjum, Aftab Ahmad</creatorcontrib><creatorcontrib>Khan, Muhammad Arif</creatorcontrib><creatorcontrib>Durrani, Aneela Zameer</creatorcontrib><creatorcontrib>Hayat, Muhammad Abid</creatorcontrib><creatorcontrib>Masood, Anjum</creatorcontrib><creatorcontrib>Sajjad, Muhammad Talha</creatorcontrib><creatorcontrib>Raza, Nadeem</creatorcontrib><title>Effect of Pre and Post-Surgical Correction of Left Displacement Abomasum on Oxidative Stress, Metabolic Status and Hematological Profile Changes in Serum of Dairy Cows of Pakistan</title><title>Pakistan journal of zoology</title><description><![CDATA[ABSTRACT This study was aimed to evaluate the oxidative stress status (malondialdehyde, MDA; catalase, CAT), metabolic status (beta hydroxybutyric acid, BHBA; nonesterified fatty acid NEFA) and hematological changes (hemoglobin, total leucocytes, red blood cells, neutrophils, platelets, lymphocytes) in serum of dairy cows before and after the surgical correction of left displacement abomasum. Twenty-six cows were divided into two groups as control (Group-A) and treatment (Group-B), each of 13 cows. Left displacement abomasum was confirmed by clinical assessment and ultrasonography, and then was surgically treated through Dirksen technique. Blood samples of both groups were collected on days 0, 7, 14, 21, and 28. Levels of various oxidative, metabolic and hematological parameters were measured by authenticated standard methods. We observed that serum levels of MDA and BHBA were higher at day 0 to day 14 (P<0.01), while the level of nonesterified fatty acid (NEFA) was higher at day 0 to day 7 (P<0.01) which dropped down to normal at day 21 (P>0.05) post-surgery in Group-B than Group-A. Moreover, CAT level in serum decreased (P<0.01) at day 0 to day 7, then it gradually increased to normal on day 14 to day 21 (P>0.05) post-surgery in Group B compared to Group A. In addition, levels of hemoglobin, total leucocytes, neutrophils were higher at day 0 to day 7 (P<0.01), while red blood cells and lymphocytes were lower at day 0 to day 14 (P<0.01) which became normal at day 28 (P>0.05) in Group-B than Group-A. The level of platelets was higher at day 0 (P<0.01), then gradually decreased to normal at day 28 in Group-B than Group-A. In conclusion, left displacement abomasum is associated with metabolic, oxidative and hematological disturbances which can be rectified through surgical correction. However, it is recommended to provide antioxidant therapy in adjunct with surgical correction for early recovery.]]></description><subject>Abdomen</subject><subject>Abomasum</subject><subject>Animals</subject><subject>Anorexia</subject><subject>Auscultation</subject><subject>Catalase</subject><subject>Cattle</subject><subject>Cytokines</subject><subject>Dairy cattle</subject><subject>Dairy farms</subject><subject>Diseases</subject><subject>Diseases and pests</subject><subject>Erythrocytes</subject><subject>Fatty acids</subject><subject>Health aspects</subject><subject>Hematology</subject><subject>Hemoglobin</subject><subject>Laboratories</subject><subject>Leukocytes</subject><subject>Leukocytes (neutrophilic)</subject><subject>Lipid peroxidation</subject><subject>Lipids</subject><subject>Lymphocytes</subject><subject>Metabolism</subject><subject>Milk</subject><subject>Motility</subject><subject>Neutrophils</subject><subject>Oxidation</subject><subject>Oxidative stress</subject><subject>Platelets</subject><subject>Serum levels</subject><subject>Stress analysis</subject><subject>Surgery</subject><subject>Ultrasonic imaging</subject><issn>0030-9923</issn><issn>0030-9923</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNpVUVFv2yAQtqZVatX1PyD1dU4B2xhrT1HarZMyNVLaZ3QmR0ZmQwa4W_e39gdHkk7aOATH6bv77viK4prRGWsbyW92fgoOhtl-9-uGU37YjOWT1m-KC0orWnYdr97-458XVzHuaF61aDiXF8XvO2NQJ-INWQUk4DZk5WMq11PYWg0DWfgQMsB6d8As0SRya-N-AI0jukTmvR8hTiPJgIefdgPJPiNZp4AxvidfMEHvB6tzBNIUjwT3OELygz8RrII3dkCy-Apui5FYR9YYDgUNuQUbXnILP-KxQfhmYwL3rjgzMES8er0vi6ePd4-L-3L58OnzYr4sdSWbVLay6UEY7LUE6PSmBomi5sxkz4iul0yYCgTQTjSUImdSC4Ega-BtfnbVZXF9qrsP_vuEManXH4-KSy6rmraNyKjZCbWFAZV1xqcAOtsGR6u9w8N0at42VSOZZCwnfDgl6OBjDGjUPtgRwotiVB2V_cujsrLqf2WrP1OKnJo</recordid><startdate>20230831</startdate><enddate>20230831</enddate><creator>Rizwan, Muhammad</creator><creator>Akbar, Hamid</creator><creator>Anjum, Aftab Ahmad</creator><creator>Khan, Muhammad Arif</creator><creator>Durrani, Aneela Zameer</creator><creator>Hayat, Muhammad Abid</creator><creator>Masood, Anjum</creator><creator>Sajjad, Muhammad Talha</creator><creator>Raza, Nadeem</creator><general>Knowledge Bylanes</general><general>AsiaNet Pakistan (Pvt) Ltd</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>7SS</scope><scope>7XB</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>LK8</scope><scope>M2P</scope><scope>M7P</scope><scope>P64</scope><scope>PATMY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PYCSY</scope><scope>Q9U</scope><scope>RC3</scope></search><sort><creationdate>20230831</creationdate><title>Effect of Pre and Post-Surgical Correction of Left Displacement Abomasum on Oxidative Stress, Metabolic Status and Hematological Profile Changes in Serum of Dairy Cows of Pakistan</title><author>Rizwan, Muhammad ; Akbar, Hamid ; Anjum, Aftab Ahmad ; Khan, Muhammad Arif ; Durrani, Aneela Zameer ; Hayat, Muhammad Abid ; Masood, Anjum ; Sajjad, Muhammad Talha ; Raza, Nadeem</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c385t-785ba6febc8aa9cd4a8e6421fd4af69b816f3a6a096500e218c66ea84a270e293</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Abdomen</topic><topic>Abomasum</topic><topic>Animals</topic><topic>Anorexia</topic><topic>Auscultation</topic><topic>Catalase</topic><topic>Cattle</topic><topic>Cytokines</topic><topic>Dairy cattle</topic><topic>Dairy farms</topic><topic>Diseases</topic><topic>Diseases and pests</topic><topic>Erythrocytes</topic><topic>Fatty acids</topic><topic>Health aspects</topic><topic>Hematology</topic><topic>Hemoglobin</topic><topic>Laboratories</topic><topic>Leukocytes</topic><topic>Leukocytes (neutrophilic)</topic><topic>Lipid peroxidation</topic><topic>Lipids</topic><topic>Lymphocytes</topic><topic>Metabolism</topic><topic>Milk</topic><topic>Motility</topic><topic>Neutrophils</topic><topic>Oxidation</topic><topic>Oxidative stress</topic><topic>Platelets</topic><topic>Serum levels</topic><topic>Stress analysis</topic><topic>Surgery</topic><topic>Ultrasonic imaging</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rizwan, Muhammad</creatorcontrib><creatorcontrib>Akbar, Hamid</creatorcontrib><creatorcontrib>Anjum, Aftab Ahmad</creatorcontrib><creatorcontrib>Khan, Muhammad Arif</creatorcontrib><creatorcontrib>Durrani, Aneela Zameer</creatorcontrib><creatorcontrib>Hayat, Muhammad Abid</creatorcontrib><creatorcontrib>Masood, Anjum</creatorcontrib><creatorcontrib>Sajjad, Muhammad Talha</creatorcontrib><creatorcontrib>Raza, Nadeem</creatorcontrib><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest Central UK/Ireland</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Environmental Science Collection</collection><collection>ProQuest Central Basic</collection><collection>Genetics Abstracts</collection><jtitle>Pakistan journal of zoology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rizwan, Muhammad</au><au>Akbar, Hamid</au><au>Anjum, Aftab Ahmad</au><au>Khan, Muhammad Arif</au><au>Durrani, Aneela Zameer</au><au>Hayat, Muhammad Abid</au><au>Masood, Anjum</au><au>Sajjad, Muhammad Talha</au><au>Raza, Nadeem</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of Pre and Post-Surgical Correction of Left Displacement Abomasum on Oxidative Stress, Metabolic Status and Hematological Profile Changes in Serum of Dairy Cows of Pakistan</atitle><jtitle>Pakistan journal of zoology</jtitle><date>2023-08-31</date><risdate>2023</risdate><volume>55</volume><issue>4</issue><spage>1755</spage><pages>1755-</pages><issn>0030-9923</issn><eissn>0030-9923</eissn><abstract><![CDATA[ABSTRACT This study was aimed to evaluate the oxidative stress status (malondialdehyde, MDA; catalase, CAT), metabolic status (beta hydroxybutyric acid, BHBA; nonesterified fatty acid NEFA) and hematological changes (hemoglobin, total leucocytes, red blood cells, neutrophils, platelets, lymphocytes) in serum of dairy cows before and after the surgical correction of left displacement abomasum. Twenty-six cows were divided into two groups as control (Group-A) and treatment (Group-B), each of 13 cows. Left displacement abomasum was confirmed by clinical assessment and ultrasonography, and then was surgically treated through Dirksen technique. Blood samples of both groups were collected on days 0, 7, 14, 21, and 28. Levels of various oxidative, metabolic and hematological parameters were measured by authenticated standard methods. We observed that serum levels of MDA and BHBA were higher at day 0 to day 14 (P<0.01), while the level of nonesterified fatty acid (NEFA) was higher at day 0 to day 7 (P<0.01) which dropped down to normal at day 21 (P>0.05) post-surgery in Group-B than Group-A. Moreover, CAT level in serum decreased (P<0.01) at day 0 to day 7, then it gradually increased to normal on day 14 to day 21 (P>0.05) post-surgery in Group B compared to Group A. In addition, levels of hemoglobin, total leucocytes, neutrophils were higher at day 0 to day 7 (P<0.01), while red blood cells and lymphocytes were lower at day 0 to day 14 (P<0.01) which became normal at day 28 (P>0.05) in Group-B than Group-A. The level of platelets was higher at day 0 (P<0.01), then gradually decreased to normal at day 28 in Group-B than Group-A. In conclusion, left displacement abomasum is associated with metabolic, oxidative and hematological disturbances which can be rectified through surgical correction. However, it is recommended to provide antioxidant therapy in adjunct with surgical correction for early recovery.]]></abstract><cop>Lahore</cop><pub>Knowledge Bylanes</pub><doi>10.17582/journal.pjz/20220221120204</doi><oa>free_for_read</oa></addata></record> |
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| subjects | Abdomen Abomasum Animals Anorexia Auscultation Catalase Cattle Cytokines Dairy cattle Dairy farms Diseases Diseases and pests Erythrocytes Fatty acids Health aspects Hematology Hemoglobin Laboratories Leukocytes Leukocytes (neutrophilic) Lipid peroxidation Lipids Lymphocytes Metabolism Milk Motility Neutrophils Oxidation Oxidative stress Platelets Serum levels Stress analysis Surgery Ultrasonic imaging |
| title | Effect of Pre and Post-Surgical Correction of Left Displacement Abomasum on Oxidative Stress, Metabolic Status and Hematological Profile Changes in Serum of Dairy Cows of Pakistan |
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