Metal–organic frameworks in diagnostics, therapeutics, and other biomedical applications
Metal–organic frameworks (MOFs) are emerging porous coordination polymers constructed by metal ions and organic linkers that have attracted numerous interests in recent years. The large surface area, high porosity, tunable size, and versatile functionality make them promising materials for cargo del...
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| Veröffentlicht in: | Journal of the Chinese Chemical Society (Taipei) 2023-06, Vol.70 (6), p.1284-1296 |
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| container_title | Journal of the Chinese Chemical Society (Taipei) |
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| creator | Hung, Pei‐Qi Lin, Pei‐Ying Wang, Xin‐Hui Ho, Ja‐an Annie |
| description | Metal–organic frameworks (MOFs) are emerging porous coordination polymers constructed by metal ions and organic linkers that have attracted numerous interests in recent years. The large surface area, high porosity, tunable size, and versatile functionality make them promising materials for cargo delivery (i.e., drugs, mRNA, dyes) and sensing (i.e., nucleic acids, small molecules, ions). In addition, the metal ions released from MOFs offer antibacterial and antifungal utility. This review presents a snapshot of current MOF‐related research, highlighting the synthesis approaches, and the various bioapplications of MOFs in terms of biosensing platforms, drug delivery, and antimicrobial agents, exposing potential for future research in the MOF field.
Metal–organic frameworks (MOFs) are emerging porous coordination polymers constructed by metal ions and organic linkers. This review presents a snapshot of current MOF‐related research, highlighting the synthesis approaches and their bioapplications in biosensing, drug delivery, and antimicrobial function. |
| doi_str_mv | 10.1002/jccs.202300101 |
| format | Article |
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Metal–organic frameworks (MOFs) are emerging porous coordination polymers constructed by metal ions and organic linkers. This review presents a snapshot of current MOF‐related research, highlighting the synthesis approaches and their bioapplications in biosensing, drug delivery, and antimicrobial function.</description><subject>Antiinfectives and antibacterials</subject><subject>antimicrobial</subject><subject>bioapplication</subject><subject>Biomedical materials</subject><subject>biosensor</subject><subject>Coordination polymers</subject><subject>drug delivery</subject><subject>Fungicides</subject><subject>Metal-organic frameworks</subject><subject>MOFs</subject><subject>Nucleic acids</subject><issn>0009-4536</issn><issn>2192-6549</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNqFkDtPwzAUhS0EEqWwMltiJeX6kYdHFPFUEQOwsFiO7YBLGgc7VdWN_8A_5JeQKghGpnvu0Tn3Sh9CxwRmBICeLbSOMwqUARAgO2hCiaBJlnKxiyYAIBKesmwfHcS4AOCMpmKCnu9sr5qvj08fXlTrNK6DWtq1D28RuxYbp15aH3un4ynuX21QnV2Nm2oN9lsLV84vrXFaNVh1XTOI3vk2HqK9WjXRHv3MKXq6vHgsr5P5_dVNeT5PNCM5SQSIlNaFBV2A1UbzvKgyYgadWW4YV6xOLdQ81yTTaa6rijORVULYwpjBYlN0Mt7tgn9f2djLhV-FdngpaUFzTgikdEjNxpQOPsZga9kFt1RhIwnILT-55Sd_-Q0FMRbWrrGbf9Lytiwf_rrfKWZ2mQ</recordid><startdate>202306</startdate><enddate>202306</enddate><creator>Hung, Pei‐Qi</creator><creator>Lin, Pei‐Ying</creator><creator>Wang, Xin‐Hui</creator><creator>Ho, Ja‐an Annie</creator><general>Wiley‐VCH Verlag GmbH & Co. KGaA</general><general>Wiley Subscription Services, Inc</general><scope>AAYXX</scope><scope>CITATION</scope><orcidid>https://orcid.org/0000-0001-6684-1118</orcidid><orcidid>https://orcid.org/0000-0003-2180-8888</orcidid></search><sort><creationdate>202306</creationdate><title>Metal–organic frameworks in diagnostics, therapeutics, and other biomedical applications</title><author>Hung, Pei‐Qi ; Lin, Pei‐Ying ; Wang, Xin‐Hui ; Ho, Ja‐an Annie</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3171-90952f8e0c80ecdc478b61d0ec6e4d34a3f5e0f47c16c57cbb4396b99e8dd16c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Antiinfectives and antibacterials</topic><topic>antimicrobial</topic><topic>bioapplication</topic><topic>Biomedical materials</topic><topic>biosensor</topic><topic>Coordination polymers</topic><topic>drug delivery</topic><topic>Fungicides</topic><topic>Metal-organic frameworks</topic><topic>MOFs</topic><topic>Nucleic acids</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hung, Pei‐Qi</creatorcontrib><creatorcontrib>Lin, Pei‐Ying</creatorcontrib><creatorcontrib>Wang, Xin‐Hui</creatorcontrib><creatorcontrib>Ho, Ja‐an Annie</creatorcontrib><collection>CrossRef</collection><jtitle>Journal of the Chinese Chemical Society (Taipei)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hung, Pei‐Qi</au><au>Lin, Pei‐Ying</au><au>Wang, Xin‐Hui</au><au>Ho, Ja‐an Annie</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Metal–organic frameworks in diagnostics, therapeutics, and other biomedical applications</atitle><jtitle>Journal of the Chinese Chemical Society (Taipei)</jtitle><date>2023-06</date><risdate>2023</risdate><volume>70</volume><issue>6</issue><spage>1284</spage><epage>1296</epage><pages>1284-1296</pages><issn>0009-4536</issn><eissn>2192-6549</eissn><abstract>Metal–organic frameworks (MOFs) are emerging porous coordination polymers constructed by metal ions and organic linkers that have attracted numerous interests in recent years. The large surface area, high porosity, tunable size, and versatile functionality make them promising materials for cargo delivery (i.e., drugs, mRNA, dyes) and sensing (i.e., nucleic acids, small molecules, ions). In addition, the metal ions released from MOFs offer antibacterial and antifungal utility. This review presents a snapshot of current MOF‐related research, highlighting the synthesis approaches, and the various bioapplications of MOFs in terms of biosensing platforms, drug delivery, and antimicrobial agents, exposing potential for future research in the MOF field.
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| ispartof | Journal of the Chinese Chemical Society (Taipei), 2023-06, Vol.70 (6), p.1284-1296 |
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| language | eng |
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| source | Wiley Online Library Journals Frontfile Complete |
| subjects | Antiinfectives and antibacterials antimicrobial bioapplication Biomedical materials biosensor Coordination polymers drug delivery Fungicides Metal-organic frameworks MOFs Nucleic acids |
| title | Metal–organic frameworks in diagnostics, therapeutics, and other biomedical applications |
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