Evaluation of Designs and Estimation Methods Under Response-Dependent Two-Phase Sampling for Genetic Association Studies

In many genetic association analyses, while the aim is to identify genetic variants associated with a given quantitative trait, budgetary constraints prevent genotyping all individuals in a cohort. Selection of individuals for genotyping according to their quantitative trait value can improve cost e...

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Veröffentlicht in:	Statistics in biosciences 2023-07, Vol.15 (2), p.510-539
Hauptverfasser:	Ryan, Brady, Nirmalkanna, Ananthika, Cigsar, Candemir, Yilmaz, Yildiz E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biostatistics Extreme values Genetic analysis Genetic diversity Genotyping Health Sciences Mathematics and Statistics Medicine Sampling Sampling designs Statistics Statistics for Life Sciences Theoretical Ecology/Statistics
Online-Zugang:	Volltext
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