Exploring the potential of chromone scaffold compounds in cancer therapy: targeting key kinase pathways

Cancer continues to be one of the leading causes of death worldwide, with an estimated 28.4 million new cases expected by 2040. Despite the efforts to treat cancer, the current therapeutic options are limited to adjuvant and neoadjuvant chemotherapy with limited alternative therapies. The discovery...

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Veröffentlicht in:	Medicinal chemistry research 2023-06, Vol.32 (6), p.1017-1038
Hauptverfasser:	Islam, Rajibul, Hossain, Md. Selim, Mock, Phooi Yan, Leong, Sze Wei, Lam, Kok Wai
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase AKT protein Anticancer properties Antitumor activity Biochemistry Biomedical and Life Sciences Biomedicine Bioorganic Chemistry Cancer Cancer therapies Chemotherapy Clinical trials DNA-dependent protein kinase Inorganic Chemistry Kinases MAP kinase Medicinal Chemistry Pharmacology/Toxicology Review Article Scaffolds TOR protein
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