Checking for CHEK2 Hereditary Mutations in Ukrainian Women: Lack of CHECK2 Variants Contribution to Breast Cancer Susceptibility

Abstract Introduction/Objective Although the role of homologous recombination repair (HRR) machinery in breast cancer susceptibility has been clearly established, the range and frequency of HRR gene mutations vary profoundly in different populations. Previously high incidence of CHEK2 (Checkpoint ki...

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Veröffentlicht in:	American journal of clinical pathology 2022-11, Vol.158 (Supplement_1), p.S40-S40
Hauptverfasser:	Sulaieva, O, Kozakov, D, Livshun, S, Matvieieva, A, Shabalkov, R
Format:	Artikel
Sprache:	eng
Schlagworte:	BRCA1 protein BRCA2 protein Breast cancer CHK2 protein Exons Homologous recombination Homologous recombination repair Kinases Mutation Susceptibility
Online-Zugang:	Volltext
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