Effects of plasticizer diisobutyl adipate on the Japanese medaka (Oryzias latipes) endocrine system

Plasticizer pollution of the water environment is one of the world's most serious environmental issues. Phthalate plasticizers can disrupt endocrine function in vertebrates. Therefore, this study analyzed thyroid‐related, reproduction‐related, and estrogen‐responsive genes in Japanese medaka (O...

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Veröffentlicht in:	Journal of applied toxicology 2023-07, Vol.43 (7), p.982-992
Hauptverfasser:	Horie, Yoshifumi, Ramaswamy, Babu Rajendran, Ríos, Juan Manuel, Yap, Chee Kong, Okamura, Hideo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipates - metabolism Animals biomarker chgH diisobutyl adipate ecotoxicity Edema Embryogenesis Embryonic growth stage endocrine disruptor Endocrine disruptors Endocrine System Estrogenic activity Estrogens Estrogens - toxicity Exposure Fish reproduction Gonadotropins Iodide peroxidase Kiss1 protein Luteinizing hormone Oryzias - metabolism Oryzias latipes Phthalates Pituitary (anterior) plasticizer Plasticizers Plasticizers - metabolism Plasticizers - toxicity Reproduction Swim bladder Swimming Thyroid Thyroid gland thyroid hormones Toxicity Vertebrates Vitellogenin vtg Water Pollutants, Chemical - metabolism Water Pollutants, Chemical - toxicity Water pollution Xenoestrogens
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