Synthesis of Some New Substituted Dihydro-5-(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1H-pyrazole) Heterocyclic Derivatives and Evaluation of Their Pharmacological Activities

A simple and efficient approach for the synthesis of dihydro-5-(4,5-dihydro-3-methyl-5-oxo-1phenyl-1 H -pyrazole) heterocyclic derivatives was developed via Knoevenagel condensation reaction followed by Michael addition using L-proline as catalyst. The newly synthesized compounds were evaluated for...

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Veröffentlicht in:	Russian journal of general chemistry 2023-04, Vol.93 (4), p.920-930
Hauptverfasser:	Rani, R. S. Priya, Venkatesh, T., Upendranath, K., Shanavaz, H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemical synthesis Chemistry Chemistry and Materials Science Chemistry/Food Science Heterocyclic compounds Molecular docking Pharmacology Proline Pyrazole Toxicity
Online-Zugang:	Volltext
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