Evaluation of Secondary Metabolites of Ageratina adenophora and Synthesis of Silver Nanoparticles for its Antibacterial and Antioxidant Activity

Synthetic antibiotics have been successfully utilized for decades against pathogenic bacteria to control infectious diseases. However, the continuous and overuse has resulted in multidrug resistant (MDR) bacterial species. Further, the negative side effects caused by commercial antibiotics also hind...

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Veröffentlicht in:Oriental journal of chemistry 2023-01, Vol.39 (1), p.102-113
Hauptverfasser: Maheswari B, Latha, Mani N, Mani N, Kavikala N, Kavikala N, Karthika S, Karthika S, Rajasudha V, Rajasudha V
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container_end_page 113
container_issue 1
container_start_page 102
container_title Oriental journal of chemistry
container_volume 39
creator Maheswari B, Latha
Mani N, Mani N
Kavikala N, Kavikala N
Karthika S, Karthika S
Rajasudha V, Rajasudha V
description Synthetic antibiotics have been successfully utilized for decades against pathogenic bacteria to control infectious diseases. However, the continuous and overuse has resulted in multidrug resistant (MDR) bacterial species. Further, the negative side effects caused by commercial antibiotics also hindered their usage. The phytochemicals produced by plants in response to adverse biotic and abiotic conditions possess significant pharmacological properties and can be an effective alternative to synthetic antibiotics. The phytochemicals of Ageratinaadenophora, served the role of reducing and stabilizing agent. Ageratinaadenophora mediated silver nanoparticles (Aa-AgNPs) were characterized using advanced spectroscopic instrumentation. The qualitative analysis by GC-MS showed Methyl ionone, 2(3H)-Naphthalenone, 4, 4a, 5, 6, 7, 8- hexahydro-4a,7,7-trimethyl-(R), Isolongifolone as the major compounds. The quantitative estimation showed leaves were rich in total phenol, flavonoids, alkaloids and tannins. The Aa-AgNPs were effective in inhibiting bacterial pathogens. Further, A.adenophora mediated nanoparticles possessed strong antioxidant activity.
doi_str_mv 10.13005/ojc/390112
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subjects Antibiotics
Antioxidants
Bacteria
Bacterial infections
Biological activity
E coli
Flavonoids
Free radicals
Herbal medicine
Hydrocarbons
Infectious diseases
Investigations
Metabolites
Microorganisms
Nanoparticles
Pathogens
Phenols
Phytochemicals
Qualitative analysis
Side effects
Silver
Solvents
Stabilizers (agents)
Streptococcus infections
title Evaluation of Secondary Metabolites of Ageratina adenophora and Synthesis of Silver Nanoparticles for its Antibacterial and Antioxidant Activity
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