A Probabilistic Approach to Evaluate the Likelihood of Artificial Genetic Modification and Its Application to SARS-CoV-2 Omicron Variant

A method to find a probability that a given bias of mutations occur naturally is proposed to test whether a newly detected virus is a product of natural evolution or a product of non-natural process such as genetic manipulation. The probability is calculated based on the neutral theory of molecular...

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Veröffentlicht in:	IPSJ Transactions on Bioinformatics 2022, Vol.15, pp.22-29
Hauptverfasser:	Kakeya, Hideki, Matsumoto, Yoshihisa
Format:	Artikel
Sprache:	eng
Schlagworte:	Bias dN/dS Evolution Genetic modification Molecular evolution Mutation Nucleotides Omicron variant point mutation Probability SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Spike protein Statistical analysis Viruses
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