Exploratory Analysis of Plasma Neurotensin as a Novel Biomarker for Early Detection of Colorectal Polyp and Cancer

Earlier detection of colorectal cancer (CRC) results in improved survival. Existing non-invasive biomarkers have suboptimal accuracy. Neurotensin (NTS) is involved in CRC carcinogenesis. This study evaluated the diagnostic potential of plasma NTS for colorectal polyps and cancers. Participants were...

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Veröffentlicht in:	Discover. Oncology 2019-06, Vol.10 (2-3), p.128-135
Hauptverfasser:	Qiu, Shengyang, Nikolaou, Stella, Fiorentino, Francesca, Rasheed, Shahnawaz, Darzi, Ara, Cunningham, David, Tekkis, Paris, Kontovounisios, Christos
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biomarkers Biomarkers, Tumor - blood Cell Biology Colonic Polyps - blood Colonic Polyps - diagnosis Colonoscopy Colorectal cancer Colorectal Neoplasms - blood Colorectal Neoplasms - diagnosis Demographics Double-Blind Method Early Detection of Cancer Endocrinology Female Humans Internal Medicine Male Medical screening Medicine Medicine & Public Health Microbiology Middle Aged Neurotensin - blood Oncology Original Paper Pathology Patients Plasma Polyps Precancerous Conditions - blood Precancerous Conditions - diagnosis Prospective Studies Regression Analysis Reproducibility of Results Risk Factors ROC Curve Sensitivity and Specificity Statistical analysis Systems Biology Tumors
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