Phytoglycogen-dsRNA nanoparticles demonstrate differential cytotoxicity and immunostimulatory potential in two ovarian cancer cell lines

Ovarian cancer is a leading cause of cancer mortality in women, and novel treatments with improved efficacy are needed to fight ovarian cancer. Double-stranded (ds) RNA, including the synthetic polyinosinic cytidylic acid (poly (I:C), has shown promise as a cancer therapeutic. Phytoglycogen derived...

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Veröffentlicht in:	Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology 2023-06, Vol.25 (6), p.104, Article 104
Hauptverfasser:	Lewis, A., Tran, A., Aldor, N. L., Jadaa, N. A., Feng, T., Moore, E., DeWitte-Orr, S. J., Poynter, S. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Biological activity Cancer Cell death Characterization and Evaluation of Materials Chemistry and Materials Science Chemokines CXCL10 protein Cytidylic acid Cytotoxicity Double-stranded RNA Immune response Immune system Immunocytochemistry Immunostimulation Inorganic Chemistry Lasers Materials Science Mortality Nanoparticles Nanotechnology Optical Devices Optics Ovarian cancer Photonics Physical Chemistry Polyinosinic:polycytidylic acid Research Paper Robustness Sensitizing Sweetcorn Toxicity Tumor cell lines
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