Microbial degradation products of lurasidone and their significance in postmortem toxicology

Recent research reported that lurasidone degrades in unpreserved ante‐mortem human whole blood inoculated with microorganisms known to dominate postmortem blood specimens. In vitro degradation occurred at a similar rate to risperidone, known to degrade in authentic postmortem specimens until below a...

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Veröffentlicht in:	Drug testing and analysis 2023-05, Vol.15 (5), p.551-565
Hauptverfasser:	Castle, Jared W., Butzbach, Danielle M., Walker, G. Stewart, Lenehan, Claire E., Reith, Frank, Costello, Samuel P., Kirkbride, K. Paul
Format:	Artikel
Sprache:	eng
Schlagworte:	Forensic Toxicology Humans LC‐QTOF‐MS lurasidone Lurasidone Hydrochloride postmortem toxicology Retrospective Studies Risperidone stability Tandem Mass Spectrometry Toxicology whole blood
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