Biphenotypic sinonasal sarcoma-A recently described entity with many mimics: A case report
Biphenotypic sinonasal sarcoma (BSNS) is a recently described, low-grade, slow-growing sarcoma with neural and myogenic features with exclusive location in sinonasal track and characteristic PAX3- MAML3 gene fusion. Differentiating this tumor from its commoner mimics needs knowledge of this entity t...
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| Veröffentlicht in: | Indian journal of pathology & microbiology 2023-04, Vol.66 (2), p.396-399 |
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| container_title | Indian journal of pathology & microbiology |
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| creator | Ingle, Abhijeet Mahendra, Nagendra Gopal Reddy, G |
| description | Biphenotypic sinonasal sarcoma (BSNS) is a recently described, low-grade, slow-growing sarcoma with neural and myogenic features with exclusive location in sinonasal track and characteristic PAX3- MAML3 gene fusion. Differentiating this tumor from its commoner mimics needs knowledge of this entity to avoid over treatment. This tumor has unique morphology, clinical course, and genetics. We report this in a 47-year-old female who was diagnosed with such a rare, solitary fibrous tumor-hemangiopericytoma (HPC-SFT) on limited initial biopsy. On subsequent excision, typical morphology and immunohistochemistry helped to clinch the diagnosis. |
| doi_str_mv | 10.4103/ijpm.ijpm_208_21 |
| format | Article |
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| subjects | Biomarkers, Tumor Biopsy Case reports Female Gene fusion Genetics Head & neck cancer Health aspects Hemangiopericytoma Humans Immunohistochemistry Middle Aged Morphology Paranasal sinus Paranasal Sinus Neoplasms - diagnosis Paranasal Sinus Neoplasms - pathology Pax3 protein PAX3 Transcription Factor Sarcoma Sarcoma - diagnosis Sarcoma - pathology Soft Tissue Neoplasms Solitary Fibrous Tumors Tumors |
| title | Biphenotypic sinonasal sarcoma-A recently described entity with many mimics: A case report |
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