Tumor microenvironment responsive nanocarriers for efficient antisense DNA delivery and enhanced chemodynamic therapy

Cancer is undoubtedly one of the major threats to mankind. Herein, we demonstrate a supramolecular approach for the design of tumour microenvironment sensitive nanoparticles composed of artemisinin, glutathione-responsive and redox-active ferrocene and antisense DNA via a single-step assembly. Assem...

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Veröffentlicht in:	Materials chemistry frontiers 2023-05, Vol.7 (9), p.1821-183
Hauptverfasser:	Raj, Gowtham, , Narendradev, Nikhil Dev, Dommeti, Viswa Kalyan Kumar, Shriwas, Saurabh, Ajay Sekhar, P. M, Jacob, Leah Susan, Srinivasula, S. Murty, Varghese, Reji
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer properties Apoptosis Cascade chemical reactions Cleavage Effectiveness Free radicals Glutathione Hydrogen peroxide Nanoparticles Tethering Therapy Tumors
Online-Zugang:	Volltext
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