Advances in synthesis and biological activities of benzotriazole analogues: A micro review
Although the first synthesis of benzotriazole was performed in the 19th century still new methods for their preparation have developed. In this micro review authors focus mostly on the various synthetic strategies developed so far to synthesize benzotriazole and its derivatives by different strategi...
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| Veröffentlicht in: | Journal of heterocyclic chemistry 2023-05, Vol.60 (5), p.705-742 |
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| container_end_page | 742 |
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| container_issue | 5 |
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| container_title | Journal of heterocyclic chemistry |
| container_volume | 60 |
| creator | Bollikolla, Hari Babu Boddapati, S. N. Murthy Thangamani, Swetha Mutchu, Baby Ramana Alam, Mohammed Mujahid Hussien, Mohamed Jonnalagadda, Sreekantha Babu |
| description | Although the first synthesis of benzotriazole was performed in the 19th century still new methods for their preparation have developed. In this micro review authors focus mostly on the various synthetic strategies developed so far to synthesize benzotriazole and its derivatives by different strategies, such as metal‐free, metal‐assisted [3 + 2] cycloaddition reactions, cyclocondensations, flow methods, heterocyclizations, and so forth. This micro review combines recent (2005–2022 till date) information on the strategies used for the synthesis of benzotriazoles. Moreover, a brief overview of the bio applications of the benzotriazole scaffold along with pharmacological activity is also discussed.
Some bioactive benzotriazole analogs. |
| doi_str_mv | 10.1002/jhet.4587 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0022-152X |
| ispartof | Journal of heterocyclic chemistry, 2023-05, Vol.60 (5), p.705-742 |
| issn | 0022-152X 1943-5193 |
| language | eng |
| recordid | cdi_proquest_journals_2806809531 |
| source | Wiley HSS Collection |
| subjects | Benzotriazole Cycloaddition Synthesis |
| title | Advances in synthesis and biological activities of benzotriazole analogues: A micro review |
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