Vascular and metabolic effects of SGLT2i and GLP-1 in heart failure patients

Alterations of endothelial function, inflammatory activation, and nitric oxide-cyclic guanosine monophosphate (NO-cGMP) pathway are involved in the pathophysiology of heart failure. Metabolic alterations have been studied in the myocardium of heart failure (HF) patients; alterations in ketone body a...

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Veröffentlicht in:	Heart failure reviews 2023-05, Vol.28 (3), p.733-744
Hauptverfasser:	Correale, Michele, Lamacchia, Olga, Ciccarelli, Michele, Dattilo, Giuseppe, Tricarico, Lucia, Brunetti, Natale Daniele
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Cardiology Cardiovascular Diseases Cardiovascular System Congestive heart failure Cyclic GMP Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - drug therapy GLP-1 receptor agonists Glucagon Glucagon-Like Peptide 1 Glucose transporter Heart Failure Humans Inflammation Medicine Medicine & Public Health Metabolism Mitochondria Myocardium Nitric oxide Protein turnover Sodium-Glucose Transporter 2 Inhibitors - pharmacology Sodium-Glucose Transporter 2 Inhibitors - therapeutic use
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