Efficiently Inhibiting Systemic Inflammatory Cascades by Fullerenes for Retarding HFD‐Fueled Atherosclerosis

Atherosclerosis accounts for major mortality of cardiac‐cerebral vascular diseases worldwide. Pathologically, persistent inflammation dominates the progression of atherosclerosis, which can be accelerated by a high‐fat diet (HFD), possibly through triggering local intestinal oxidative stress and ens...

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Veröffentlicht in:	Advanced healthcare materials 2023-04, Vol.12 (11), p.e2202161-n/a
Hauptverfasser:	Su, Sheng'e, Zhen, Mingming, Zhou, Chen, Cao, Xinran, Sun, Zihao, Xu, Yuan, Li, Lei, Jia, Wang, Wu, Zhanfeng, Wang, Chunru
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta Apolipoprotein E Arteriosclerosis Atherosclerosis Atherosclerosis - drug therapy Atherosclerosis - metabolism Collagen Coronary artery disease Diet, High-Fat - adverse effects Digestive system Drug therapy fullerene Fullerenes Fullerenes - adverse effects Gastrointestinal tract gut barrier Heart diseases High fat diet Homeostasis Inflammation Inflammation - drug therapy Inflammation - metabolism Intestine Lipids Lipopolysaccharides Mice Mice, Inbred C57BL Nanoparticles Oxidative stress Plaques Side effects TLR4 protein Toll-like receptors Toxicity Vascular diseases
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