Joint Modeling of Biomarker Cascades Along An Unobserved Disease Progression with Differentiate Covariate Effects: An Application in Alzheimer's Disease

Alzheimer's Disease (AD) research has shifted to focus on biomarker trajectories and their potential use in understanding the underlying AD-related pathological process. A conceptual framework was proposed in modern AD research that hypothesized biomarker cascades as a result of underlying AD p...

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Veröffentlicht in:arXiv.org 2024-09
Hauptverfasser: Tang, Zhuojun, Zhu, Yuxin, Zhang, Kexin, Wang, Zheyu
Format: Artikel
Sprache:eng
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