Late‐Stage Functionalisation of Pyridine‐Containing Bioactive Molecules: Recent Strategies and Perspectives

Late‐Stage Functionalisation (LSF) is an innovative technique that has been successfully applied to the C−H diversification of pharmaceuticals. However, LSF of the pyridine ring in drug‐like molecules is often unselective. As a result, a mixture of structurally related products is obtained, thus mak...

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Veröffentlicht in:	European journal of organic chemistry 2023-04, Vol.26 (16), p.n/a
Hauptverfasser:	Failla, Mattia, Lombardo, Giacomo W., Orlando, Paolo, Fiorito, Daniele, Bombonato, Elena, Ronchi, Paolo, Passarella, Daniele, Fasano, Valerio
Format:	Artikel
Sprache:	eng
Schlagworte:	Functionalisation Late-stage N-heterocycle Natural products Pyridines Selectivity
Online-Zugang:	Volltext
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