The genotypes of glutathione peroxidase 1 (GPx1) (Rs1050450) affect some biomarker levels in the breast cancer patients

Polymorphisms in the antioxidant enzymes have a role in the development of breast cancer. Glutathione peroxidase 1 (GPx1) is one of the antioxidant enzymes that play an effective role in oxidative stress resistance. Pro198Leu (C → T) polymorphism affected GPx1 effectiveness, which might further play...

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Veröffentlicht in:	Journal of biotech research 2023-01, Vol.14, p.153-159
Hauptverfasser:	Abdulabbas, Hadi Sajid, Mohamed, Asma'a Hassan, Al-Imari, Mustafa Jawad, Al-Mawlah, Yasir Haider, Shaheed, Salah Hashim
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants Biomarkers Breast cancer Catalase Deoxyribonucleic acid DNA Electrophoresis Enzymes Free radicals Gel electrophoresis Gene polymorphism Genetic diversity Genotype & phenotype Genotypes Glutathione Glutathione peroxidase Heterozygotes Lipid peroxidation Lipids Oxidation resistance Oxidative stress Peroxidase Polymerase chain reaction Polymorphism Proteins Restriction fragment length polymorphism Risk management Risk reduction Single-nucleotide polymorphism Superoxide dismutase Ultraviolet radiation
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