Modulation of nutrient precursors for controlling metabolic inhibitors by genome‐scale flux balance analysis

Therapeutic protein productivity and glycosylation pattern highly rely on cell metabolism. Cell culture medium composition and feeding strategy are critical to regulate cell metabolism. In this study, the relationship between toxic metabolic inhibitors and their nutrient precursors was explored to i...

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Veröffentlicht in:Biotechnology progress 2023-03, Vol.39 (2), p.e3313-n/a
Hauptverfasser: Hoang, Duc, Kuang, Bingyu, Liang, George, Wang, Zhao, Yoon, Seongkyu
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Sprache:eng
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