A dynamic DNA tetrahedron framework for active targeting

An active targeting strategy-enabled DNA tetrahedron delivery vehicle could facilitate stable drug encapsulation and stimuli-responsive on-demand release, building a universal platform for different drug delivery requirements. Owing to the excellent biocompatible nature, programmability and remarkab...

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Veröffentlicht in:	Nature protocols 2023-04, Vol.18 (4), p.1028-1055
Hauptverfasser:	Tian, Taoran, Zhang, Tao, Shi, Sirong, Gao, Yang, Cai, Xiaoxiao, Lin, Yunfeng
Format:	Artikel
Sprache:	eng
Schlagworte:	631/154/152 631/1647/350/2093 631/61/54/152 Analytical Chemistry Anticancer properties Antitumor activity Biocompatibility Biological activity Biological effects Biological Techniques Biomedical and Life Sciences Computational Biology/Bioinformatics Conformation Deoxyribonucleic acid Design DNA DNA - chemistry Drug delivery Drug Delivery Systems Electrophoresis Encapsulation Environmental effects Exoskeleton Exoskeletons Fabrication Gel electrophoresis Hybridization Inflammation Life Sciences Microarrays Nanostructure Nanostructures - chemistry Onsite Organic Chemistry Permeability pH effects Polyacrylamide Protocol Extension Stimuli Tetrahedra Titration Verification
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