The Effect of Perfluorocarbon Nanoparticles on Blood As a Cellular System
— The effect of perfluorocarbon (PFC) nanoparticles on the functioning of blood cells is considered. Evidence is presented indicating that emulsified PFC nanoparticles in small volumes affect gas transport function of blood, increasing the rate of oxygen diffusion from erythrocytes to tissues. It wa...
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| Veröffentlicht in: | Biochemistry (Moscow). Supplement series A, Membrane and cell biology Membrane and cell biology, 2023-03, Vol.17 (1), p.20-27 |
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| container_title | Biochemistry (Moscow). Supplement series A, Membrane and cell biology |
| container_volume | 17 |
| creator | Kuznetsova, I. N. Lyanguzov, A. Yu |
| description | —
The effect of perfluorocarbon (PFC) nanoparticles on the functioning of blood cells is considered. Evidence is presented indicating that emulsified PFC nanoparticles in small volumes affect gas transport function of blood, increasing the rate of oxygen diffusion from erythrocytes to tissues. It was found that PFC nanoparticles also affect the state of blood cells (erythrocytes, leukocytes, and platelets) in a dose-dependent manner. It was assumed that depending on the emulsion dose, that is, the density of nanoparticles in the surrounding space of cells, the reaction of receptor apparatus can cause activation or deterioration of their functioning. |
| doi_str_mv | 10.1134/S1990747823010051 |
| format | Article |
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The effect of perfluorocarbon (PFC) nanoparticles on the functioning of blood cells is considered. Evidence is presented indicating that emulsified PFC nanoparticles in small volumes affect gas transport function of blood, increasing the rate of oxygen diffusion from erythrocytes to tissues. It was found that PFC nanoparticles also affect the state of blood cells (erythrocytes, leukocytes, and platelets) in a dose-dependent manner. It was assumed that depending on the emulsion dose, that is, the density of nanoparticles in the surrounding space of cells, the reaction of receptor apparatus can cause activation or deterioration of their functioning.</description><identifier>ISSN: 1990-7478</identifier><identifier>EISSN: 1990-7494</identifier><identifier>DOI: 10.1134/S1990747823010051</identifier><language>eng</language><publisher>Moscow: Pleiades Publishing</publisher><subject>Biomedical and Life Sciences ; Cell Biology ; Diffusion rate ; Erythrocytes ; Gas transport ; Leukocytes ; Life Sciences ; Nanoparticles ; Perfluorocarbons ; Reviews</subject><ispartof>Biochemistry (Moscow). Supplement series A, Membrane and cell biology, 2023-03, Vol.17 (1), p.20-27</ispartof><rights>Pleiades Publishing, Ltd. 2023. ISSN 1990-7478, Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology, 2023, Vol. 17, No. 1, pp. 20–27. © Pleiades Publishing, Ltd., 2023.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c268t-b379ce8a119cbd459968c4ff03052c8afba35c7001f6193a14a42e7fe8d4f7ee3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1134/S1990747823010051$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1134/S1990747823010051$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids></links><search><creatorcontrib>Kuznetsova, I. N.</creatorcontrib><creatorcontrib>Lyanguzov, A. Yu</creatorcontrib><title>The Effect of Perfluorocarbon Nanoparticles on Blood As a Cellular System</title><title>Biochemistry (Moscow). Supplement series A, Membrane and cell biology</title><addtitle>Biochem. Moscow Suppl. Ser. A</addtitle><description>—
The effect of perfluorocarbon (PFC) nanoparticles on the functioning of blood cells is considered. Evidence is presented indicating that emulsified PFC nanoparticles in small volumes affect gas transport function of blood, increasing the rate of oxygen diffusion from erythrocytes to tissues. It was found that PFC nanoparticles also affect the state of blood cells (erythrocytes, leukocytes, and platelets) in a dose-dependent manner. It was assumed that depending on the emulsion dose, that is, the density of nanoparticles in the surrounding space of cells, the reaction of receptor apparatus can cause activation or deterioration of their functioning.</description><subject>Biomedical and Life Sciences</subject><subject>Cell Biology</subject><subject>Diffusion rate</subject><subject>Erythrocytes</subject><subject>Gas transport</subject><subject>Leukocytes</subject><subject>Life Sciences</subject><subject>Nanoparticles</subject><subject>Perfluorocarbons</subject><subject>Reviews</subject><issn>1990-7478</issn><issn>1990-7494</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNp1kE9LAzEUxIMoWKsfwFvA82r-7SY51lK1UFRoPS_Z7Iu2pJs12T3027tlRQ_i6Q3D_ObBIHRNyS2lXNytqdZECqkYJ5SQnJ6gydHKpNDi9EdLdY4uUtoRUnBRFBO03HwAXjgHtsPB4VeIzvchBmtiFRr8bJrQmthtrYeEB-Peh1DjWcIGz8H73puI14fUwf4SnTnjE1x93yl6e1hs5k_Z6uVxOZ-tMssK1WUVl9qCMpRqW9Ui17pQVjhHOMmZVcZVhudWEkJdQTU3VBjBQDpQtXASgE_RzdjbxvDZQ-rKXehjM7wsmdQsF0oqMqTomLIxpBTBlW3c7k08lJSUx8XKP4sNDBuZNGSbd4i_zf9DX5_rbEI</recordid><startdate>20230301</startdate><enddate>20230301</enddate><creator>Kuznetsova, I. N.</creator><creator>Lyanguzov, A. Yu</creator><general>Pleiades Publishing</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope></search><sort><creationdate>20230301</creationdate><title>The Effect of Perfluorocarbon Nanoparticles on Blood As a Cellular System</title><author>Kuznetsova, I. N. ; Lyanguzov, A. Yu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c268t-b379ce8a119cbd459968c4ff03052c8afba35c7001f6193a14a42e7fe8d4f7ee3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Biomedical and Life Sciences</topic><topic>Cell Biology</topic><topic>Diffusion rate</topic><topic>Erythrocytes</topic><topic>Gas transport</topic><topic>Leukocytes</topic><topic>Life Sciences</topic><topic>Nanoparticles</topic><topic>Perfluorocarbons</topic><topic>Reviews</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kuznetsova, I. N.</creatorcontrib><creatorcontrib>Lyanguzov, A. Yu</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><jtitle>Biochemistry (Moscow). Supplement series A, Membrane and cell biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kuznetsova, I. N.</au><au>Lyanguzov, A. Yu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Effect of Perfluorocarbon Nanoparticles on Blood As a Cellular System</atitle><jtitle>Biochemistry (Moscow). Supplement series A, Membrane and cell biology</jtitle><stitle>Biochem. Moscow Suppl. Ser. A</stitle><date>2023-03-01</date><risdate>2023</risdate><volume>17</volume><issue>1</issue><spage>20</spage><epage>27</epage><pages>20-27</pages><issn>1990-7478</issn><eissn>1990-7494</eissn><abstract>—
The effect of perfluorocarbon (PFC) nanoparticles on the functioning of blood cells is considered. Evidence is presented indicating that emulsified PFC nanoparticles in small volumes affect gas transport function of blood, increasing the rate of oxygen diffusion from erythrocytes to tissues. It was found that PFC nanoparticles also affect the state of blood cells (erythrocytes, leukocytes, and platelets) in a dose-dependent manner. It was assumed that depending on the emulsion dose, that is, the density of nanoparticles in the surrounding space of cells, the reaction of receptor apparatus can cause activation or deterioration of their functioning.</abstract><cop>Moscow</cop><pub>Pleiades Publishing</pub><doi>10.1134/S1990747823010051</doi><tpages>8</tpages></addata></record> |
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| ispartof | Biochemistry (Moscow). Supplement series A, Membrane and cell biology, 2023-03, Vol.17 (1), p.20-27 |
| issn | 1990-7478 1990-7494 |
| language | eng |
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| source | SpringerLink Journals |
| subjects | Biomedical and Life Sciences Cell Biology Diffusion rate Erythrocytes Gas transport Leukocytes Life Sciences Nanoparticles Perfluorocarbons Reviews |
| title | The Effect of Perfluorocarbon Nanoparticles on Blood As a Cellular System |
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