Hepatoprotective activity of lycopene in experimental paracetamol-induced liver injury in rats

Aim: To evaluate the hepatoprotective effects of lycopene pretreatment in paracetamol-induced liver damage (PILD). Methods: Wistar rats were administered oral lycopene (4 mg/kg/day) by gastric lavage for 8 days. Subsequently, 3 g/kg paracetamol was administered on day 8. After 24 and 72 h, animals w...

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Veröffentlicht in:Revista colombiana de ciencias químico-farmacéuticas 2022, Vol.51 (3)
Hauptverfasser: Bonilha Dezena, Renan Marcel, da Silva, Gustavo Henrique, Silva Gonçalves, Gisele Mara
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Sprache:eng
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