Timescales of Cell Membrane Fusion Mediated by SARS-CoV2 Spike Protein and its Receptor ACE2

In this manuscript we describe the investigation of the SARS-CoV2 membrane fusion timescale by means of small-angle neutron scattering (SANS) using hydrogen/deuterium contrast variation. After the successful production of virus-like vesicles and human-host-cell-like vesicles we were able to follow t...

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Veröffentlicht in:	arXiv.org 2023-03
Hauptverfasser:	Hayward, Dominic, Dubey, Purushottam S, Marie-Sousai Appavou, Holderer, Olaf, Henrich Frielinghaus, Prevost, Sylvain, Farago, Bela, Sokolova, Anna, Zolnierczuk, Piotr, Heiner von Buttlar, Braun, Peter, Joachim Jakob Bugert, Ehmann, Rosina, Jaksch, Sebastian
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell membranes Deuteration Deuterium Neutron scattering Phospholipids Proteins Receptors Severe acute respiratory syndrome Time constant Vesicles Viral diseases Viruses
Online-Zugang:	Volltext
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