Studies on imidazo[2,1-b][1,3]benzothiazole derivatives as new radiosensitizers

The synthesis and characterization of potent 7-substituted-2-(4-substitutedphenyl)imidazo[2,1- b ][1,3]benzothiazoles as effective radiosensitizers and anticarcinogenic compound is reported. The activity is determined against human liver cancer Hep G2 cell line, two parental melanoma cell lines (hum...

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Veröffentlicht in:	SN applied sciences 2020-11, Vol.2 (11), p.1902, Article 1902
Hauptverfasser:	Majalakere, Krishnakishore, Kunhana, Sarojini Balladka, Rao, Shama, Kalal, Bhuvanesh Sukhlal, Badiadka, Narayana, Sanjeev, Ganesh, Holla, Bantwal Shivaram
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer properties Antitumor activity Apoptosis Applied and Technical Physics Benzothiazole Cancer therapies Carbon Chemistry/Food Science Chemistry: Pharmaceutical DNA fragmentation Drug dosages Earth Sciences Engineering Environment Hepatocellular carcinoma Hepatocytes Hypoxia Liver cancer Materials Science Medical Medicinal and Clinical Chemistry Melanoma Radiation Radiosensitizers Research Article Sulfonamides
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