Evaluation of photodynamic therapy effects of novel zinc (II) phthalocyanine through a possible interaction with toll‐like receptor signaling pathway

In this work, 3‐({6‐[3‐(dimethylamino)phenoxy]hexyl}oxy)phthalonitrile (2) and the target zinc (II) phthalocyanine (3) and its ammonium derivative (3a) are synthesized, and the phototoxic effects of 3a were examined using different methods on A549 lung cancer cells. Then, the toll‐like receptor (TLR...

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Veröffentlicht in:	Applied organometallic chemistry 2023-04, Vol.37 (4), p.n/a
Hauptverfasser:	Barut, Burak, Yalçın, Can Özgür, Altun, Yasemin, Akkaya, Didem, Barut, Elif Nur, Baş, Hüseyin, Biyiklioglu, Zekeriya
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Cell death Chemistry Light irradiation Lung cancer Photodynamic therapy phthalocyanines Receptors Signaling toll‐like receptor Zinc
Online-Zugang:	Volltext
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