Growth factor regulation of cell growth and proliferation in the nervous system

This article discusses a novel intracrine mechanism of growth-factor action in the nervous system whereby fibroblast growth factor-2 (FGF-2) and its receptor accumulate in the cell nucleus and act as mediators in the control of cell growth and proliferation. In human and rat brain the levels and sub...

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Veröffentlicht in:	Molecular neurobiology 1997-12, Vol.15 (3), p.257-283
Hauptverfasser:	Stachowiak, M. K, Moffett, J, Maher, P, Tucholski, J, Stachowiak, E. K
Format:	Artikel
Sprache:	eng ; jpn
Schlagworte:	Astrocytes Brain tumors Cell growth Cell proliferation Cerebellum Cytoplasm Fibroblast growth factor 2 Fibroblast growth factor receptor 1 Glioma Growth factors Kinases Localization Nervous system Neural crest Neuronal-glial interactions Transfection
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