Hepatopulmonary syndrome in noncirrhotic patients with chronic viral hepatitis
Background Hepatopulmonary syndrome (HPS) is hypoxemia and functional intrapulmonary right-to-left shunts in patients with liver disease. It is a well-known complication of liver cirrhosis, portal hypertension, and acute liver failure. Aim The aim of this study was to determine the extent to which p...
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Veröffentlicht in: | The Egyptian Journal of Bronchology 2014-12, Vol.8 (2), p.175-180 |
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creator | El-Habashy, Mahmoud M. Khamis, Ahmed A. Kamel, Mahmoud Essa, Abdallah Shehab-Eldin, Walid Shaban, Mohamed |
description | Background
Hepatopulmonary syndrome (HPS) is hypoxemia and functional intrapulmonary right-to-left shunts in patients with liver disease. It is a well-known complication of liver cirrhosis, portal hypertension, and acute liver failure.
Aim
The aim of this study was to determine the extent to which pulmonary functions were affected and the possible existence of HPS in noncirrhotic patients with chronic viral hepatitis.
Patients and methods
Lung function tests were carried out on 60 patients with chronic viral hepatitis (43 with hepatitis C and 17 with hepatitis B). All hypoxemic patients or patients with reduced diffusion capacity were subjected to contrast echocardiography to demonstrate intrapulmonary shunting.
Results
Twelve patients showed pulmonary dysfunction. Only seven of 60 patients (11.67%) showed hypoxemia. Intrapulmonary shunting was observed in three of those 12 patients. Two of these patients fulfilled the diagnostic criteria of HPS.
Conclusion
HPS exists in some patients with chronic viral hepatitis and is thus not restricted to patients with end-stage liver disease.
Egypt J Broncho
2014 8:175–180 |
doi_str_mv | 10.4103/1687-8426.145728 |
format | Article |
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Hepatopulmonary syndrome (HPS) is hypoxemia and functional intrapulmonary right-to-left shunts in patients with liver disease. It is a well-known complication of liver cirrhosis, portal hypertension, and acute liver failure.
Aim
The aim of this study was to determine the extent to which pulmonary functions were affected and the possible existence of HPS in noncirrhotic patients with chronic viral hepatitis.
Patients and methods
Lung function tests were carried out on 60 patients with chronic viral hepatitis (43 with hepatitis C and 17 with hepatitis B). All hypoxemic patients or patients with reduced diffusion capacity were subjected to contrast echocardiography to demonstrate intrapulmonary shunting.
Results
Twelve patients showed pulmonary dysfunction. Only seven of 60 patients (11.67%) showed hypoxemia. Intrapulmonary shunting was observed in three of those 12 patients. Two of these patients fulfilled the diagnostic criteria of HPS.
Conclusion
HPS exists in some patients with chronic viral hepatitis and is thus not restricted to patients with end-stage liver disease.
Egypt J Broncho
2014 8:175–180</description><identifier>ISSN: 1687-8426</identifier><identifier>EISSN: 2314-8551</identifier><identifier>DOI: 10.4103/1687-8426.145728</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Hepatitis ; Hypoxemia ; Liver diseases ; Medicine & Public Health ; Original Article</subject><ispartof>The Egyptian Journal of Bronchology, 2014-12, Vol.8 (2), p.175-180</ispartof><rights>2014 Egyptian Journal of Bronchology 2014</rights><rights>2014 Egyptian Journal of Bronchology 2014. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c1538-9dea47e283a03b8d46e19ec5a5c78271a9196872faaa12c022521b09a69742113</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.4103/1687-8426.145728$$EPDF$$P50$$Gspringer$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://doi.org/10.4103/1687-8426.145728$$EHTML$$P50$$Gspringer$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,864,27922,27923,41118,42187,51574</link.rule.ids></links><search><creatorcontrib>El-Habashy, Mahmoud M.</creatorcontrib><creatorcontrib>Khamis, Ahmed A.</creatorcontrib><creatorcontrib>Kamel, Mahmoud</creatorcontrib><creatorcontrib>Essa, Abdallah</creatorcontrib><creatorcontrib>Shehab-Eldin, Walid</creatorcontrib><creatorcontrib>Shaban, Mohamed</creatorcontrib><title>Hepatopulmonary syndrome in noncirrhotic patients with chronic viral hepatitis</title><title>The Egyptian Journal of Bronchology</title><addtitle>Egypt J Bronchol</addtitle><description>Background
Hepatopulmonary syndrome (HPS) is hypoxemia and functional intrapulmonary right-to-left shunts in patients with liver disease. It is a well-known complication of liver cirrhosis, portal hypertension, and acute liver failure.
Aim
The aim of this study was to determine the extent to which pulmonary functions were affected and the possible existence of HPS in noncirrhotic patients with chronic viral hepatitis.
Patients and methods
Lung function tests were carried out on 60 patients with chronic viral hepatitis (43 with hepatitis C and 17 with hepatitis B). All hypoxemic patients or patients with reduced diffusion capacity were subjected to contrast echocardiography to demonstrate intrapulmonary shunting.
Results
Twelve patients showed pulmonary dysfunction. Only seven of 60 patients (11.67%) showed hypoxemia. Intrapulmonary shunting was observed in three of those 12 patients. Two of these patients fulfilled the diagnostic criteria of HPS.
Conclusion
HPS exists in some patients with chronic viral hepatitis and is thus not restricted to patients with end-stage liver disease.
Egypt J Broncho
2014 8:175–180</description><subject>Hepatitis</subject><subject>Hypoxemia</subject><subject>Liver diseases</subject><subject>Medicine & Public Health</subject><subject>Original Article</subject><issn>1687-8426</issn><issn>2314-8551</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNp1kM1LAzEQxYMoWGrvHgOet2ay-dqjFLWFohc9hzRN3UibrMlW6X9vlhU9eRqY-b03Mw-hayBzBqS-BaFkpRgVc2BcUnWGJrQGVinO4RxNfseXaJaz3xAmBAgm1QQ9LV1n-tgd94cYTDrhfArbFA8O-4BDDNan1MbeW1ww70Kf8ZfvW2zbFEPpfvpk9rgdTHzv8xW62Jl9drOfOkWvD_cvi2W1fn5cLe7WlQVeq6rZOsOko6o2pN6oLRMOGme54VYqKsE00JSb6c4YA9QSSjmFDWmMaCSjAPUU3Yy-XYofR5d7_R6PKZSVmkrF6fCgKhQZKZtizsntdJf8oXypgeghOD0ko4dk9BhckcAoyQUNby79Gf-r-QaNDG9g</recordid><startdate>20141201</startdate><enddate>20141201</enddate><creator>El-Habashy, Mahmoud M.</creator><creator>Khamis, Ahmed A.</creator><creator>Kamel, Mahmoud</creator><creator>Essa, Abdallah</creator><creator>Shehab-Eldin, Walid</creator><creator>Shaban, Mohamed</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>20141201</creationdate><title>Hepatopulmonary syndrome in noncirrhotic patients with chronic viral hepatitis</title><author>El-Habashy, Mahmoud M. ; Khamis, Ahmed A. ; Kamel, Mahmoud ; Essa, Abdallah ; Shehab-Eldin, Walid ; Shaban, Mohamed</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1538-9dea47e283a03b8d46e19ec5a5c78271a9196872faaa12c022521b09a69742113</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Hepatitis</topic><topic>Hypoxemia</topic><topic>Liver diseases</topic><topic>Medicine & Public Health</topic><topic>Original Article</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>El-Habashy, Mahmoud M.</creatorcontrib><creatorcontrib>Khamis, Ahmed A.</creatorcontrib><creatorcontrib>Kamel, Mahmoud</creatorcontrib><creatorcontrib>Essa, Abdallah</creatorcontrib><creatorcontrib>Shehab-Eldin, Walid</creatorcontrib><creatorcontrib>Shaban, Mohamed</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><jtitle>The Egyptian Journal of Bronchology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>El-Habashy, Mahmoud M.</au><au>Khamis, Ahmed A.</au><au>Kamel, Mahmoud</au><au>Essa, Abdallah</au><au>Shehab-Eldin, Walid</au><au>Shaban, Mohamed</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hepatopulmonary syndrome in noncirrhotic patients with chronic viral hepatitis</atitle><jtitle>The Egyptian Journal of Bronchology</jtitle><stitle>Egypt J Bronchol</stitle><date>2014-12-01</date><risdate>2014</risdate><volume>8</volume><issue>2</issue><spage>175</spage><epage>180</epage><pages>175-180</pages><issn>1687-8426</issn><eissn>2314-8551</eissn><abstract>Background
Hepatopulmonary syndrome (HPS) is hypoxemia and functional intrapulmonary right-to-left shunts in patients with liver disease. It is a well-known complication of liver cirrhosis, portal hypertension, and acute liver failure.
Aim
The aim of this study was to determine the extent to which pulmonary functions were affected and the possible existence of HPS in noncirrhotic patients with chronic viral hepatitis.
Patients and methods
Lung function tests were carried out on 60 patients with chronic viral hepatitis (43 with hepatitis C and 17 with hepatitis B). All hypoxemic patients or patients with reduced diffusion capacity were subjected to contrast echocardiography to demonstrate intrapulmonary shunting.
Results
Twelve patients showed pulmonary dysfunction. Only seven of 60 patients (11.67%) showed hypoxemia. Intrapulmonary shunting was observed in three of those 12 patients. Two of these patients fulfilled the diagnostic criteria of HPS.
Conclusion
HPS exists in some patients with chronic viral hepatitis and is thus not restricted to patients with end-stage liver disease.
Egypt J Broncho
2014 8:175–180</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><doi>10.4103/1687-8426.145728</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Hepatitis Hypoxemia Liver diseases Medicine & Public Health Original Article |
title | Hepatopulmonary syndrome in noncirrhotic patients with chronic viral hepatitis |
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