Association of CYP1A2 and GST gene variants with asthma in cases presenting with allergic chronic rhinosinusitis

Background Inter-individual differences in regulation and activity of xenobiotic metabolizing enzymes (XMEs) CYP1A and GST might cause distinct susceptibility to chronic rhinosinusitis (CRS) phenotypes that need to be explored. Therefore, the present study aimed to evaluate the role and risk of CYP1...

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Veröffentlicht in:	Egyptian Journal of Medical Human Genetics 2023-12, Vol.24 (1), p.22-13, Article 22
Hauptverfasser:	Jangala, Madhavi, Manche, Santoshi Kumari, Katika, Madhu Mohan, Koralla, Raja Meghanadh, Akka, Jyothy
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergies Allergy Analysis Asthma Chronic rhinosinusitis CYP1A protein CYP1A2 protein Cytochrome Cytochrome P-450 Cytochrome P450 Cytochrome P450 1A2 Disease Enzymes Gene polymorphism Genes Genetic analysis Genetic research Genotype & phenotype Glutathione transferase Glutathione-S-transferase GSTM1 protein GSTT1 protein Haplotype Haplotypes Health risk assessment Medicine Medicine & Public Health Oxidative stress Phenotypes Polymerase chain reaction Polymorphism Regression analysis Restriction fragment length polymorphism Rhinitis Rhinosinusitis Sinusitis
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