Multicomponent synthesis of spiro 1,3,4‐thiadiazolines with anticancer activity by using deep eutectic solvent under microwave irradiation

This work describes a simple and efficient alternative method for obtaining 1,3,4‐thiadialzolinic spirocompounds, combining the use of deep eutectic solvents (DES) with microwave irradiation in a one‐pot process. A series of DES based on different acids was explored as a solvent in a three‐component...

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Veröffentlicht in:	Journal of heterocyclic chemistry 2023-03, Vol.60 (3), p.392-405
Hauptverfasser:	Castro, Aleff, Andrade, Isadora Maria Gouveia, Coelho, Maísa Cavalcanti, Costa, Daniel Pereira, Moreira, Dayse das Neves, Maia, Rachel Azevedo, Lima, Gesiane da Silva, Santos, Gabriel Franco, Vaz, Boniek Gontijo, Militão, Gardênia Carmen Gadelha, Silva, Paulo Bruno Norberto, Vasconcellos, Mário Luiz Araujo de Almeida, Lima‐Junior, Claudio Gabriel
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer properties Choline Irradiation Oxalic acid Solvents Synthesis
Online-Zugang:	Volltext
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