HFIP-assisted reductive C–S, C–N, and C–X coupling of carbonyl compounds: a combined computational and experimental mechanistic study

Owing to the importance of carbon–heteroatom bonds in synthetic organic chemistry and pharmaceuticals, developing reliable and catalyst-free methods for their construction sets a significant goal of high practical value for modern chemistry. The currently known approaches typically rely on pre-funct...

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Veröffentlicht in:	Organic Chemistry Frontiers 2023-02, Vol.10 (5), p.1275-1282
Hauptverfasser:	Khan, Jabir, Tyagi, Aparna, Ghosh, Dibyajyoti, Hazra, Chinmoy Kumar
Format:	Artikel
Sprache:	eng
Schlagworte:	Biocompatibility Carbonyl compounds Carbonyl groups Carbonyls Catalysts Chemical reduction Computer applications Coupling (molecular) Direct reduction Functional groups Nucleophiles Organic chemistry Reagents Reducing agents Substrates
Online-Zugang:	Volltext
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