Thermo-responsive Chitosan/β-glycerophosphate hydrogels directly post-loading anti-inflammatory diclofenac sodium

In this study, diclofenac sodium (DS) is post-loaded directly into thermo-sensitive hydrogels fabricated from chitosan and β-glycerophosphate (GP) for temperature-controlled-release application at the inflammatory sites. Experiments analyzing the effect of GP concentration and simulated physiologica...

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Veröffentlicht in:	Journal of sol-gel science and technology 2023-02, Vol.105 (2), p.451-460
Hauptverfasser:	Do, Nga H. N., Pham, Thinh H., Le, Phung K., Ha, Anh C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Ceramics Chemistry and Materials Science Chitosan Composites Diclofenac Dissolution Genipin Glass Glycerophosphate Hydrogels Inorganic Chemistry Materials Science Nanotechnology Natural Materials Nonsteroidal anti-inflammatory drugs Optical and Electronic Materials Original Paper: Sol-gel and hybrid materials for biological and health (medical) applications Physiological effects Pore size Sodium Sol-gel processes Solvents Swelling ratio
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