Long-term Copper Exposure Induces Mitochondrial Dynamics Disorder and Mitophagy in the Cerebrum of Pigs

Copper (Cu) is an essential trace element for growth and development in most organisms. However, environmental exposure to high doses of Cu can damage multiple organs. To investigate the underlying mechanism of Cu toxicity on mitochondrial dynamics and mitophagy in the cerebrum of pigs, 60 30-day-ol...

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Veröffentlicht in:	Biological trace element research 2023-03, Vol.201 (3), p.1197-1204
Hauptverfasser:	Li, Xinrun, Bai, Yuman, Huo, Haihua, Wu, Haitong, Liao, Jianzhao, Han, Qingyue, Zhang, Hui, Hu, Lianmei, Li, Ying, Pan, Jiaqiang, Tang, Zhaoxin, Guo, Jianying
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry Biomedical and Life Sciences Biotechnology Body organs Cerebrum Cerebrum - metabolism Copper Copper - toxicity Degeneration Dynamics Gene expression Hogs Life Sciences Mitochondria Mitochondrial Dynamics Mitophagy Nutrition Oncology Protein Kinases - genetics Protein Kinases - metabolism Proteins PTEN-induced putative kinase RNA, Messenger Swine Toxicity Toxicology Trace elements Trace elements (nutrients) Ubiquitin-Protein Ligases - genetics Ubiquitin-Protein Ligases - metabolism
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