Life-threatening altered mental status secondary to memantine in an adolescent undergoing cranial radiotherapy for medulloblastoma

Introduction Memantine is used for neurocognitive protection in patients undergoing cranial radiotherapy for central nervous system tumors and is reported to be well-tolerated. Case report Presented is a case of memantine-induced altered mental status requiring an intensive care unit admission. An 1...

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Veröffentlicht in:	Journal of oncology pharmacy practice 2023-03, Vol.29 (2), p.469-472
Hauptverfasser:	Kim, Kristine N, Shah, Yash B, Croy, Colleen, Lustig, Robert A, LaRiviere, Michael, Kotch, Chelsea
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Brain Neoplasms - drug therapy Central nervous system Cerebellar Neoplasms Child Clinical trials Cognition Cranial Irradiation - adverse effects Cranial Irradiation - methods Dexamethasone Humans Male Medulloblastoma Medulloblastoma - drug therapy Medulloblastoma - radiotherapy Memantine Memantine - therapeutic use Morphine Neuroimaging Patients Pediatrics Radiation therapy Skull Teenagers Toxicity Valproic acid
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