Bioinspired synthesize of CuO nanoparticles using Cylindrospermum stagnale for antibacterial, anticancer and larvicidal applications
Biologically synthesized metal-oxide nanoparticles (NPs) are in focus for their multifarious applications. In the current study, the green synthesis of copper oxide NPs (CuO NPs) is achieved using the fresh biomass of Cylindrospermum stagnale after its molecular characterization. Physical characteri...
Gespeichert in:
| Veröffentlicht in: | Applied nanoscience 2023, Vol.13 (1), p.917-927 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 927 |
|---|---|
| container_issue | 1 |
| container_start_page | 917 |
| container_title | Applied nanoscience |
| container_volume | 13 |
| creator | Sonbol, Hana AlYahya, Sami Ameen, Fuad Alsamhary, Khawla Alwakeel, Suaad Al-Otaibi, Sohailah Korany, Shereen |
| description | Biologically synthesized metal-oxide nanoparticles (NPs) are in focus for their multifarious applications. In the current study, the green synthesis of copper oxide NPs (CuO NPs) is achieved using the fresh biomass of
Cylindrospermum stagnale
after its molecular characterization. Physical characterization of CuO NPs by several analytical techniques including UV–Vis analysis, FT-IR spectroscopy, SEM and TEM microscopy revealed spherical shaped crystalline CuO-NPs capped by functional groups of cyanobacterium biomolecules with slight aggregation. CuO NPs were found significantly antimicrobial against pathogens with MICs of 1.5, 2.4, 1.7, 2.5, and 0.6 mM against
Candida albicans
,
Klebsiella pneumoniae
,
Enterobacter cloacae
,
Pseudomonas aeruginosa
,
Escherichia coli
, respectively. Moreover, cyanobacterium-capped CuO NPs were cytotoxic against HepG2 cell line and effective against larvae of
Aedes ageypti
,
Anopheles subpictus
Grassi and
Culex quinquefasciatus
. The synthesized CuO NPs were effective due to their high surface area and fairly small size 12.21 nm. Due to adequate biological activities of cyanobacterium CuO NPs even at lower concentrations, we prospect these NPs for clinical applications. |
| doi_str_mv | 10.1007/s13204-021-01940-2 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2771071177</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2771071177</sourcerecordid><originalsourceid>FETCH-LOGICAL-c249t-79df0d4c9360f8ece882c8dade1f636c6a641fe87d7efce21dfa98e4b0a752853</originalsourceid><addsrcrecordid>eNp9UDtPwzAQthBIVKV_gMkSKwHbeTgZIeIlVWKB2bra5-IqdYKdIJWZH07aINi45e70PXT3EXLO2RVnTF5HngqWJUzwhPEqY4k4IjPBK5bkOZfHvzOrTskixg0bK89kkeYz8nXrWudj5wIaGne-f8PoPpG2ltbDM_Xg2w5C73SDkQ7R-TWtd43zJrSxw7AdtjT2sPbQILVtoOB7twLdY3DQXB5WDV7jHjG0gfDhtDPQUOi6ZoR61_p4Rk4sNBEXP31OXu_vXurHZPn88FTfLBMtsqpPZGUsM5mu0oLZEjWWpdClAYPcFmmhCygybrGURqLVKLixUJWYrRjIXJR5OicXk28X2vcBY6827RDG26MSUnImOZdyZImJpccfY0CruuC2EHaKM7UPXE2BqzFwdQhciVGUTqI4kv0aw5_1P6pvHyyHUg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2771071177</pqid></control><display><type>article</type><title>Bioinspired synthesize of CuO nanoparticles using Cylindrospermum stagnale for antibacterial, anticancer and larvicidal applications</title><source>Springer Nature - Complete Springer Journals</source><creator>Sonbol, Hana ; AlYahya, Sami ; Ameen, Fuad ; Alsamhary, Khawla ; Alwakeel, Suaad ; Al-Otaibi, Sohailah ; Korany, Shereen</creator><creatorcontrib>Sonbol, Hana ; AlYahya, Sami ; Ameen, Fuad ; Alsamhary, Khawla ; Alwakeel, Suaad ; Al-Otaibi, Sohailah ; Korany, Shereen</creatorcontrib><description>Biologically synthesized metal-oxide nanoparticles (NPs) are in focus for their multifarious applications. In the current study, the green synthesis of copper oxide NPs (CuO NPs) is achieved using the fresh biomass of
Cylindrospermum stagnale
after its molecular characterization. Physical characterization of CuO NPs by several analytical techniques including UV–Vis analysis, FT-IR spectroscopy, SEM and TEM microscopy revealed spherical shaped crystalline CuO-NPs capped by functional groups of cyanobacterium biomolecules with slight aggregation. CuO NPs were found significantly antimicrobial against pathogens with MICs of 1.5, 2.4, 1.7, 2.5, and 0.6 mM against
Candida albicans
,
Klebsiella pneumoniae
,
Enterobacter cloacae
,
Pseudomonas aeruginosa
,
Escherichia coli
, respectively. Moreover, cyanobacterium-capped CuO NPs were cytotoxic against HepG2 cell line and effective against larvae of
Aedes ageypti
,
Anopheles subpictus
Grassi and
Culex quinquefasciatus
. The synthesized CuO NPs were effective due to their high surface area and fairly small size 12.21 nm. Due to adequate biological activities of cyanobacterium CuO NPs even at lower concentrations, we prospect these NPs for clinical applications.</description><identifier>ISSN: 2190-5509</identifier><identifier>EISSN: 2190-5517</identifier><identifier>DOI: 10.1007/s13204-021-01940-2</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Antiinfectives and antibacterials ; Biomolecules ; Chemistry and Materials Science ; Copper oxides ; Cyanobacteria ; E coli ; Enterobacter cloacae ; Functional groups ; Infrared spectroscopy ; Klebsiella ; Larvae ; Materials Science ; Membrane Biology ; Metal oxides ; Nanochemistry ; Nanoparticles ; Nanotechnology ; Nanotechnology and Microengineering ; Original Article ; Pseudomonas aeruginosa ; Synthesis</subject><ispartof>Applied nanoscience, 2023, Vol.13 (1), p.917-927</ispartof><rights>King Abdulaziz City for Science and Technology 2021</rights><rights>King Abdulaziz City for Science and Technology 2021.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c249t-79df0d4c9360f8ece882c8dade1f636c6a641fe87d7efce21dfa98e4b0a752853</citedby><cites>FETCH-LOGICAL-c249t-79df0d4c9360f8ece882c8dade1f636c6a641fe87d7efce21dfa98e4b0a752853</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s13204-021-01940-2$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s13204-021-01940-2$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids></links><search><creatorcontrib>Sonbol, Hana</creatorcontrib><creatorcontrib>AlYahya, Sami</creatorcontrib><creatorcontrib>Ameen, Fuad</creatorcontrib><creatorcontrib>Alsamhary, Khawla</creatorcontrib><creatorcontrib>Alwakeel, Suaad</creatorcontrib><creatorcontrib>Al-Otaibi, Sohailah</creatorcontrib><creatorcontrib>Korany, Shereen</creatorcontrib><title>Bioinspired synthesize of CuO nanoparticles using Cylindrospermum stagnale for antibacterial, anticancer and larvicidal applications</title><title>Applied nanoscience</title><addtitle>Appl Nanosci</addtitle><description>Biologically synthesized metal-oxide nanoparticles (NPs) are in focus for their multifarious applications. In the current study, the green synthesis of copper oxide NPs (CuO NPs) is achieved using the fresh biomass of
Cylindrospermum stagnale
after its molecular characterization. Physical characterization of CuO NPs by several analytical techniques including UV–Vis analysis, FT-IR spectroscopy, SEM and TEM microscopy revealed spherical shaped crystalline CuO-NPs capped by functional groups of cyanobacterium biomolecules with slight aggregation. CuO NPs were found significantly antimicrobial against pathogens with MICs of 1.5, 2.4, 1.7, 2.5, and 0.6 mM against
Candida albicans
,
Klebsiella pneumoniae
,
Enterobacter cloacae
,
Pseudomonas aeruginosa
,
Escherichia coli
, respectively. Moreover, cyanobacterium-capped CuO NPs were cytotoxic against HepG2 cell line and effective against larvae of
Aedes ageypti
,
Anopheles subpictus
Grassi and
Culex quinquefasciatus
. The synthesized CuO NPs were effective due to their high surface area and fairly small size 12.21 nm. Due to adequate biological activities of cyanobacterium CuO NPs even at lower concentrations, we prospect these NPs for clinical applications.</description><subject>Antiinfectives and antibacterials</subject><subject>Biomolecules</subject><subject>Chemistry and Materials Science</subject><subject>Copper oxides</subject><subject>Cyanobacteria</subject><subject>E coli</subject><subject>Enterobacter cloacae</subject><subject>Functional groups</subject><subject>Infrared spectroscopy</subject><subject>Klebsiella</subject><subject>Larvae</subject><subject>Materials Science</subject><subject>Membrane Biology</subject><subject>Metal oxides</subject><subject>Nanochemistry</subject><subject>Nanoparticles</subject><subject>Nanotechnology</subject><subject>Nanotechnology and Microengineering</subject><subject>Original Article</subject><subject>Pseudomonas aeruginosa</subject><subject>Synthesis</subject><issn>2190-5509</issn><issn>2190-5517</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNp9UDtPwzAQthBIVKV_gMkSKwHbeTgZIeIlVWKB2bra5-IqdYKdIJWZH07aINi45e70PXT3EXLO2RVnTF5HngqWJUzwhPEqY4k4IjPBK5bkOZfHvzOrTskixg0bK89kkeYz8nXrWudj5wIaGne-f8PoPpG2ltbDM_Xg2w5C73SDkQ7R-TWtd43zJrSxw7AdtjT2sPbQILVtoOB7twLdY3DQXB5WDV7jHjG0gfDhtDPQUOi6ZoR61_p4Rk4sNBEXP31OXu_vXurHZPn88FTfLBMtsqpPZGUsM5mu0oLZEjWWpdClAYPcFmmhCygybrGURqLVKLixUJWYrRjIXJR5OicXk28X2vcBY6827RDG26MSUnImOZdyZImJpccfY0CruuC2EHaKM7UPXE2BqzFwdQhciVGUTqI4kv0aw5_1P6pvHyyHUg</recordid><startdate>2023</startdate><enddate>2023</enddate><creator>Sonbol, Hana</creator><creator>AlYahya, Sami</creator><creator>Ameen, Fuad</creator><creator>Alsamhary, Khawla</creator><creator>Alwakeel, Suaad</creator><creator>Al-Otaibi, Sohailah</creator><creator>Korany, Shereen</creator><general>Springer International Publishing</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>2023</creationdate><title>Bioinspired synthesize of CuO nanoparticles using Cylindrospermum stagnale for antibacterial, anticancer and larvicidal applications</title><author>Sonbol, Hana ; AlYahya, Sami ; Ameen, Fuad ; Alsamhary, Khawla ; Alwakeel, Suaad ; Al-Otaibi, Sohailah ; Korany, Shereen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c249t-79df0d4c9360f8ece882c8dade1f636c6a641fe87d7efce21dfa98e4b0a752853</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Antiinfectives and antibacterials</topic><topic>Biomolecules</topic><topic>Chemistry and Materials Science</topic><topic>Copper oxides</topic><topic>Cyanobacteria</topic><topic>E coli</topic><topic>Enterobacter cloacae</topic><topic>Functional groups</topic><topic>Infrared spectroscopy</topic><topic>Klebsiella</topic><topic>Larvae</topic><topic>Materials Science</topic><topic>Membrane Biology</topic><topic>Metal oxides</topic><topic>Nanochemistry</topic><topic>Nanoparticles</topic><topic>Nanotechnology</topic><topic>Nanotechnology and Microengineering</topic><topic>Original Article</topic><topic>Pseudomonas aeruginosa</topic><topic>Synthesis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sonbol, Hana</creatorcontrib><creatorcontrib>AlYahya, Sami</creatorcontrib><creatorcontrib>Ameen, Fuad</creatorcontrib><creatorcontrib>Alsamhary, Khawla</creatorcontrib><creatorcontrib>Alwakeel, Suaad</creatorcontrib><creatorcontrib>Al-Otaibi, Sohailah</creatorcontrib><creatorcontrib>Korany, Shereen</creatorcontrib><collection>CrossRef</collection><jtitle>Applied nanoscience</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sonbol, Hana</au><au>AlYahya, Sami</au><au>Ameen, Fuad</au><au>Alsamhary, Khawla</au><au>Alwakeel, Suaad</au><au>Al-Otaibi, Sohailah</au><au>Korany, Shereen</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Bioinspired synthesize of CuO nanoparticles using Cylindrospermum stagnale for antibacterial, anticancer and larvicidal applications</atitle><jtitle>Applied nanoscience</jtitle><stitle>Appl Nanosci</stitle><date>2023</date><risdate>2023</risdate><volume>13</volume><issue>1</issue><spage>917</spage><epage>927</epage><pages>917-927</pages><issn>2190-5509</issn><eissn>2190-5517</eissn><abstract>Biologically synthesized metal-oxide nanoparticles (NPs) are in focus for their multifarious applications. In the current study, the green synthesis of copper oxide NPs (CuO NPs) is achieved using the fresh biomass of
Cylindrospermum stagnale
after its molecular characterization. Physical characterization of CuO NPs by several analytical techniques including UV–Vis analysis, FT-IR spectroscopy, SEM and TEM microscopy revealed spherical shaped crystalline CuO-NPs capped by functional groups of cyanobacterium biomolecules with slight aggregation. CuO NPs were found significantly antimicrobial against pathogens with MICs of 1.5, 2.4, 1.7, 2.5, and 0.6 mM against
Candida albicans
,
Klebsiella pneumoniae
,
Enterobacter cloacae
,
Pseudomonas aeruginosa
,
Escherichia coli
, respectively. Moreover, cyanobacterium-capped CuO NPs were cytotoxic against HepG2 cell line and effective against larvae of
Aedes ageypti
,
Anopheles subpictus
Grassi and
Culex quinquefasciatus
. The synthesized CuO NPs were effective due to their high surface area and fairly small size 12.21 nm. Due to adequate biological activities of cyanobacterium CuO NPs even at lower concentrations, we prospect these NPs for clinical applications.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><doi>10.1007/s13204-021-01940-2</doi><tpages>11</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2190-5509 |
| ispartof | Applied nanoscience, 2023, Vol.13 (1), p.917-927 |
| issn | 2190-5509 2190-5517 |
| language | eng |
| recordid | cdi_proquest_journals_2771071177 |
| source | Springer Nature - Complete Springer Journals |
| subjects | Antiinfectives and antibacterials Biomolecules Chemistry and Materials Science Copper oxides Cyanobacteria E coli Enterobacter cloacae Functional groups Infrared spectroscopy Klebsiella Larvae Materials Science Membrane Biology Metal oxides Nanochemistry Nanoparticles Nanotechnology Nanotechnology and Microengineering Original Article Pseudomonas aeruginosa Synthesis |
| title | Bioinspired synthesize of CuO nanoparticles using Cylindrospermum stagnale for antibacterial, anticancer and larvicidal applications |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-02T16%3A49%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Bioinspired%20synthesize%20of%20CuO%20nanoparticles%20using%20Cylindrospermum%20stagnale%20for%20antibacterial,%20anticancer%20and%20larvicidal%20applications&rft.jtitle=Applied%20nanoscience&rft.au=Sonbol,%20Hana&rft.date=2023&rft.volume=13&rft.issue=1&rft.spage=917&rft.epage=927&rft.pages=917-927&rft.issn=2190-5509&rft.eissn=2190-5517&rft_id=info:doi/10.1007/s13204-021-01940-2&rft_dat=%3Cproquest_cross%3E2771071177%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2771071177&rft_id=info:pmid/&rfr_iscdi=true |