Primary amine C–N bond cleavage for the synthesis of multi-substituted pyridine and pyrrole derivatives

An efficient synthesis of multi-substituted pyridines and pyrroles from aryl methyl ketones with 1-amino-2-methylpropan-2-ol and 1,2-diamino-2-methylpropane, respectively, has been developed. The reactions each involved cleavage of one C–N bond and formation of two new bonds, namely a C–C bond and C...

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Veröffentlicht in:	Organic Chemistry Frontiers 2023-01, Vol.10 (3), p.780-785
Hauptverfasser:	Zhang, Ruiqin, Ding, Yuxin, Ma, Renchao, Xiao, Xuqiong, Chen, Rener, Wang, Lei, Ma, Yongmin
Format:	Artikel
Sprache:	eng
Schlagworte:	Cleavage Covalent bonds Ketones Organic chemistry Pyridines Pyrroles Substitutes Synthesis
Online-Zugang:	Volltext
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